Crystal Structure of Thermus thermophilus HB8 Argininosuccinate Synthetase in complex with inhibitors

Summary for 1KOR

Related1KH1 1KH2 1KH3
DescriptorArgininosuccinate Synthetase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ARGININE, ... (5 entities in total)
Functional Keywordsligase, riken structural genomics/proteomics initiative, rsgi, structural genomics
Biological sourceThermus thermophilus
Cellular locationCytoplasm (Probable) P59846
Total number of polymer chains4
Total molecular weight182701.94
Goto, M.,Nakajima, Y.,Hirotsu, K.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2001-12-22, release date: 2002-04-03, Last modification date: 2011-07-13)
Primary citation
Goto, M.,Nakajima, Y.,Hirotsu, K.
Crystal structure of argininosuccinate synthetase from Thermus thermophilus HB8. Structural basis for the catalytic action.
J.Biol.Chem., 277:15890-15896, 2002
PubMed: 11844799 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M112430200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25417 0.4% 6.4% 4.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-25