6P9V
Crystal Structure of hMAT Mutant K289L
Summary for 6P9V
| Entry DOI | 10.2210/pdb6p9v/pdb |
| Descriptor | S-adenosylmethionine synthase isoform type-2, ADENOSINE, POTASSIUM ION, ... (6 entities in total) |
| Functional Keywords | adenosyl transferase, adomet synthase, natural product enzyme, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 46382.55 |
| Authors | Miller, M.D.,Xu, W.,Huber, T.D.,Clinger, J.A.,Liu, Y.,Thorson, J.S.,Phillips Jr., G.N. (deposition date: 2019-06-10, release date: 2020-04-22, Last modification date: 2023-10-11) |
| Primary citation | Huber, T.D.,Clinger, J.A.,Liu, Y.,Xu, W.,Miller, M.D.,Phillips Jr., G.N.,Thorson, J.S. Methionine Adenosyltransferase Engineering to Enable Bioorthogonal Platforms for AdoMet-Utilizing Enzymes. Acs Chem.Biol., 15:695-705, 2020 Cited by PubMed: 32091873DOI: 10.1021/acschembio.9b00943 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.051 Å) |
Structure validation
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