6P9V
Crystal Structure of hMAT Mutant K289L
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | S-adenosylmethionine synthase isoform type-2 | polymer | 415 | 45875.9 | 1 | UniProt (P31153) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) In PDB | Homo sapiens (Human) | AdoMet synthase 2,Methionine adenosyltransferase 2,MAT 2,Methionine adenosyltransferase II,MAT-II |
2 | A | ADENOSINE | non-polymer | 267.2 | 1 | Chemie (ADN) | |||
3 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | A | PYROPHOSPHATE 2- | non-polymer | 176.0 | 1 | Chemie (POP) | |||
6 | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A: 1 - 395 (UniProt: P31153)
PDB | External Database | Details |
---|---|---|
Met -19 | - | initiating methionine |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Leu 289 | Lys 289 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 45875.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 506.6 | |
All* | Total formula weight | 46382.6 |