PDB: 92212 resultsInfo pagesStatus searchChemie searchBIRD

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4ND7	Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the closed form Descriptor: BETA-MERCAPTOETHANOL, SODIUM ION, Tyrosine--tRNA ligase Authors: Cooley, R.B, Driggers, C.M, Karplus, P.A, Mehl, R.A. Deposit date: 2013-10-25 Release date: 2014-03-19 Last modified: 2019-07-17 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Basis of Improved Second-Generation 3-Nitro-tyrosine tRNA Synthetases. Biochemistry, 53, 2014
1MLN	STRUCTURAL AND FUNCTIONAL EFFECTS OF APOLAR MUTATIONS OF VAL68(E11) IN MYOGLOBIN Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION Authors: Quillin, M.L, Phillips Jr, G.N. Deposit date: 1994-06-15 Release date: 1994-08-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and functional effects of apolar mutations of the distal valine in myoglobin. J.Mol.Biol., 245, 1995
5OE6	Crystal structure of the N-terminal domain of PqsA in complex with 6-fluoroanthraniloyl-AMP (crystal form 1) Descriptor: 6-fluoroanthraniloyl-AMP, Anthranilate--CoA ligase, TRIETHYLENE GLYCOL Authors: Witzgall, F, Ewert, W, Blankenfeldt, W. Deposit date: 2017-07-07 Release date: 2017-09-06 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Structures of the N-Terminal Domain of PqsA in Complex with Anthraniloyl- and 6-Fluoroanthraniloyl-AMP: Substrate Activation in Pseudomonas Quinolone Signal (PQS) Biosynthesis. Chembiochem, 18, 2017
5IJB	The ligand-free structure of the mouse TLR4/MD-2 complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ... Authors: Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. Deposit date: 2016-03-01 Release date: 2016-04-27 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.91 Å) Cite: TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc.Natl.Acad.Sci.USA, 113, 2016
2ZK1	Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2 Descriptor: (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid, Peroxisome proliferator-activated receptor gamma Authors: Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K. Deposit date: 2008-03-12 Release date: 2009-02-24 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.61 Å) Cite: Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids J.Mol.Biol., 385, 2009
8BYL	Cryo-EM structure of SKP1-SKP2-CKS1 from the SCFSKP2 E3 ligase complex Descriptor: Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, S-phase kinase-associated protein 1, ... Authors: Rowland, R.J, Salamina, M, Endicott, J.A, Noble, M.E.M. Deposit date: 2022-12-13 Release date: 2023-06-28 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1. Sci Rep, 13, 2023
3HOD	Crystal structure of the PPARgamma-LBD complexed with a new aryloxy-3phenylpropanoic acid Descriptor: (2S)-2-(4-benzylphenoxy)-3-phenylpropanoic acid, Peroxisome proliferator-activated receptor gamma Authors: Pochetti, G, Montanari, R, Mazza, F, Loiodice, F, Fracchiolla, G, Laghezza, A, Lavecchia, A, Novellino, E. Deposit date: 2009-06-02 Release date: 2009-10-27 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.1 Å) Cite: New 2-Aryloxy-3-phenyl-propanoic Acids As Peroxisome Proliferator-Activated Receptors alpha/gamma Dual Agonists with Improved Potency and Reduced Adverse Effects on Skeletal Muscle Function J.Med.Chem., 52, 2009
3DCQ	LECB (PA-LII) in complex with the synthetic ligand 2G0 Descriptor: (2S)-1-[(2S)-6-amino-2-({[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]acetyl}amino)hexanoyl]-N-[(1S)-1-carbamoyl-3-methylbutyl]pyrrolidine-2-carboxamide, CALCIUM ION, Fucose-binding lectin PA-IIL Authors: Johansson, E.M, Crusz, S.A, Kolomiets, E, Buts, L, Kadam, R.U, Cacciarini, M, Bartels, K.M, Diggle, S.P, Camara, M, Williams, P, Loris, R, Nativi, C, Rosenau, F, Jaeger, K.E, Darbre, T, Reymond, J.L. Deposit date: 2008-06-04 Release date: 2009-01-13 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB. Chem.Biol., 15, 2008
2ZK2	Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with glutathion conjugated 15-deoxy-delta12,14-prostaglandin J2 Descriptor: (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid, GLUTATHIONE, Peroxisome proliferator-activated receptor gamma Authors: Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K. Deposit date: 2008-03-12 Release date: 2009-02-24 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids J.Mol.Biol., 385, 2009
5OE5	Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 3) Descriptor: 5'-O-[(S)-[(2-aminobenzoyl)oxy](hydroxy)phosphoryl]adenosine, Anthranilate--CoA ligase, DI(HYDROXYETHYL)ETHER Authors: Witzgall, F, Ewert, W, Blankenfeldt, W. Deposit date: 2017-07-07 Release date: 2017-09-06 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Structures of the N-Terminal Domain of PqsA in Complex with Anthraniloyl- and 6-Fluoroanthraniloyl-AMP: Substrate Activation in Pseudomonas Quinolone Signal (PQS) Biosynthesis. Chembiochem, 18, 2017
8P11	X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL003044. Descriptor: 4-(4-chlorophenyl)piperidin-4-ol, Acetylcholine-binding protein, CHLORIDE ION, ... Authors: Cederfelt, D, Boronat, P, Dobritzsch, D, Hennig, S, Fitzgerald, E.A, de Esch, I.J.P, Danielson, U.H. Deposit date: 2023-05-11 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Elucidating the regulation of ligand gated ion channels via biophysical studies of ligand-induced conformational dynamics of acetylcholine binding proteins To Be Published
8P1F	X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL001909. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-azanyl-1-phenyl-piperidine-4-carboxylic acid, Acetylcholine-binding protein Authors: Cederfelt, D, Boronat, P, Dobritzsch, D, Hennig, S, Fitzgerald, E.A, de Esch, I.J.P, Danielson, U.H. Deposit date: 2023-05-12 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Elucidating the regulation of ligand gated ion channels via biophysical studies of ligand-induced conformational dynamics of acetylcholine binding proteins To Be Published
8P1E	X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL001613. Descriptor: 1-[4-(trifluoromethyl)pyridin-2-yl]piperazine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine-binding protein, ... Authors: Cederfelt, D, Boronat, P, Dobritzsch, D, Hennig, S, Fitzgerald, E.A, de Esch, I.J.P, Danielson, U.H. Deposit date: 2023-05-11 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Elucidating the regulation of ligand gated ion channels via biophysical studies of ligand-induced conformational dynamics of acetylcholine binding proteins To Be Published
2AUR	F97V (no ligand bound) Descriptor: Globin I, PROTOPORPHYRIN IX CONTAINING FE Authors: Knapp, J.E, Bonham, M.A, Gibson, Q.H, Nichols, J.C, Royer Jr, W.E. Deposit date: 2005-08-28 Release date: 2006-03-28 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Residue F4 plays a key role in modulating oxygen affinity and cooperativity in Scapharca dimeric hemoglobin Biochemistry, 44, 2005
2AV3	F97L- no ligand Descriptor: Globin I, PROTOPORPHYRIN IX CONTAINING FE Authors: Knapp, J.E, Bonham, M.A, Gibson, Q.H, Nichols, J.C, Royer Jr, W.E. Deposit date: 2005-08-29 Release date: 2006-03-28 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Residue F4 plays a key role in modulating oxygen affinity and cooperativity in Scapharca dimeric hemoglobin Biochemistry, 44, 2005
3D6G	Fc fragment of IgG1 (Herceptin) with protein-A mimetic peptide dendrimer ligand. Descriptor: 2-[[(2S)-2,6-bis[[(2S)-2,6-bis[[(2R)-2-[[(2R,3R)-2-[[(2R)-2-amino-5-carbamimidamido-pentanoyl]amino]-3-hydroxy-butanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]hexanoyl]amino]hexanoyl]amino]ethanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region Authors: Bujacz, A.D, Redzynia, I, Bujacz, G.D, Dinon, F, Pengo, P, Fassina, G. Deposit date: 2008-05-19 Release date: 2009-06-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural characterization of a Protein A mimetic peptide dendrimer bound to human IgG. J.Phys.Chem.B, 113, 2009
8DFM	Ectodomain of full-length wild-type KIT-SCF dimers Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... Authors: Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J. Deposit date: 2022-06-22 Release date: 2023-03-29 Last modified: 2023-04-05 Method: ELECTRON MICROSCOPY (3.45 Å) Cite: Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention. Proc.Natl.Acad.Sci.USA, 120, 2023
8DFQ	Ectodomain of full-length KIT(T417I,delta418-419)-SCF dimers Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... Authors: Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J. Deposit date: 2022-06-22 Release date: 2023-03-29 Last modified: 2023-04-05 Method: ELECTRON MICROSCOPY (3.96 Å) Cite: Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention. Proc.Natl.Acad.Sci.USA, 120, 2023
8DFP	Ectodomain of full-length KIT(DupA502,Y503)-SCF dimers Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... Authors: Bertoletti, N, Krimmer, S.G, Mi, W, Schlessinger, J. Deposit date: 2022-06-22 Release date: 2023-03-29 Last modified: 2023-04-05 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention. Proc.Natl.Acad.Sci.USA, 120, 2023
5OE3	Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 1) Descriptor: 1,2-ETHANEDIOL, 5'-O-[(S)-[(2-aminobenzoyl)oxy](hydroxy)phosphoryl]adenosine, ACETATE ION, ... Authors: Witzgall, F, Ewert, W, Blankenfeldt, W. Deposit date: 2017-07-07 Release date: 2017-09-06 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Structures of the N-Terminal Domain of PqsA in Complex with Anthraniloyl- and 6-Fluoroanthraniloyl-AMP: Substrate Activation in Pseudomonas Quinolone Signal (PQS) Biosynthesis. Chembiochem, 18, 2017
5OE4	Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 2) Descriptor: 5'-O-[(S)-[(2-aminobenzoyl)oxy](hydroxy)phosphoryl]adenosine, Anthranilate--CoA ligase Authors: Witzgall, F, Ewert, W, Blankenfeldt, W. Deposit date: 2017-07-07 Release date: 2017-09-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.904 Å) Cite: Structures of the N-Terminal Domain of PqsA in Complex with Anthraniloyl- and 6-Fluoroanthraniloyl-AMP: Substrate Activation in Pseudomonas Quinolone Signal (PQS) Biosynthesis. Chembiochem, 18, 2017
1DUO	SPERM WHALE METAQUOMYOGLOBIN PROXIMAL HISTIDINE MUTANT H93G WITH 1-METHYLIMIDAZOLE AS PROXIMAL LIGAND. Descriptor: 1-METHYLIMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, SPERM WHALE METAQUOMYOGLOBIN VARIANT H93G Authors: Barrick, D, Dahlquist, F.W. Deposit date: 2000-01-18 Release date: 2000-02-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Trans-substitution of the proximal hydrogen bond in myoglobin: I. Structural consequences of hydrogen bond deletion. Proteins, 39, 2000
5K0S	Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis in complex with inhibitor Chem 1312 Descriptor: 2-({3-[(3,5-dichlorobenzyl)amino]propyl}amino)quinolin-4(1H)-one, Methionine--tRNA ligase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-05-17 Release date: 2016-05-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis. Plos One, 11, 2016
1MLJ	STRUCTURAL AND FUNCTIONAL EFFECTS OF APOLAR MUTATIONS OF VAL68(E11) IN MYOGLOBIN Descriptor: CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Quillin, M.L, Phillips Jr, G.N. Deposit date: 1994-06-15 Release date: 1994-08-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and functional effects of apolar mutations of the distal valine in myoglobin. J.Mol.Biol., 245, 1995
2ZK5	Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with nitro-233 Descriptor: 3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid, Peroxisome proliferator-activated receptor gamma Authors: Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K. Deposit date: 2008-03-12 Release date: 2009-02-24 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids J.Mol.Biol., 385, 2009

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