3DCQ

LECB (PA-LII) in complex with the synthetic ligand 2G0

Summary for 3DCQ

Entry DOI	10.2210/pdb3dcq/pdb
Related	1OUX 1OXC
Descriptor	Fucose-binding lectin PA-IIL, CALCIUM ION, (2S)-1-[(2S)-6-amino-2-({[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]acetyl}amino)hexanoyl]-N-[(1S)-1-carbamoyl-3-methylbutyl]pyrrolidine-2-carboxamide, ... (4 entities in total)
Functional Keywords	lectin, carbohydrate, sugar binding protein
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	4
Total formula weight	49434.06
Authors	Johansson, E.M.,Crusz, S.A.,Kolomiets, E.,Buts, L.,Kadam, R.U.,Cacciarini, M.,Bartels, K.M.,Diggle, S.P.,Camara, M.,Williams, P.,Loris, R.,Nativi, C.,Rosenau, F.,Jaeger, K.E.,Darbre, T.,Reymond, J.L. (deposition date: 2008-06-04, release date: 2009-01-13, Last modification date: 2023-11-01)
Primary citation	Johansson, E.M.,Crusz, S.A.,Kolomiets, E.,Buts, L.,Kadam, R.U.,Cacciarini, M.,Bartels, K.M.,Diggle, S.P.,Camara, M.,Williams, P.,Loris, R.,Nativi, C.,Rosenau, F.,Jaeger, K.E.,Darbre, T.,Reymond, J.L. Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB. Chem.Biol., 15:1249-1257, 2008 Cited by PubMed: 19101469 DOI: 10.1016/j.chembiol.2008.10.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation