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4ZU9
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BU of 4zu9 by Molmil
Crystal structure of bacterial selenocysteine-specific elongation factor EF-Sec
Descriptor: CYSTEINE, Elongation factor SelB, MAGNESIUM ION, ...
Authors:Itoh, Y, Sekine, S, Yokoyama, S.
Deposit date:2015-05-15
Release date:2015-09-23
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (3.191 Å)
Cite:Crystal structure of the full-length bacterial selenocysteine-specific elongation factor SelB
Nucleic Acids Res., 43, 2015
1J53
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BU of 1j53 by Molmil
Structure of the N-terminal Exonuclease Domain of the Epsilon Subunit of E.coli DNA Polymerase III at pH 8.5
Descriptor: 1,2-ETHANEDIOL, DNA polymerase III, epsilon chain, ...
Authors:Hamdan, S, Carr, P.D, Brown, S.E, Ollis, D.L, Dixon, N.E.
Deposit date:2002-01-22
Release date:2002-10-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for Proofreading during Replication of the Escherichia coli Chromosome
Structure, 10, 2002
1VSE
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BU of 1vse by Molmil
ASV INTEGRASE CORE DOMAIN WITH MG(II) COFACTOR AND HEPES LIGAND, LOW MG CONCENTRATION FORM
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, INTEGRASE
Authors:Bujacz, G, Jaskolski, M, Alexandratos, J, Wlodawer, A.
Deposit date:1995-11-29
Release date:1996-04-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations.
Structure, 4, 1996
4V0L
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BU of 4v0l by Molmil
Crystal structure of the CrARL6DN in the GTP bound form
Descriptor: ARF-LIKE SMALL GTPASE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Mourao, A, Lorentzen, E.
Deposit date:2014-09-17
Release date:2014-11-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:Structural Basis for Membrane Targeting of the Bbsome by Arl6
Nat.Struct.Mol.Biol., 21, 2014
1VUB
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BU of 1vub by Molmil
CCDB, A TOPOISOMERASE POISON FROM E. COLI
Descriptor: CCDB, CHLORIDE ION
Authors:Loris, R, Dao-Thi, M.-H, Bahasi, E.M, Van Melderen, L, Poortmans, F, Liddington, R, Couturier, M, Wyns, L.
Deposit date:1998-04-17
Release date:1998-07-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of CcdB, a topoisomerase poison from E. coli.
J.Mol.Biol., 285, 1999
1MS6
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BU of 1ms6 by Molmil
Dipeptide Nitrile Inhibitor Bound to Cathepsin S.
Descriptor: Cathepsin S, MORPHOLINE-4-CARBOXYLIC ACID [1S-(2-BENZYLOXY-1R-CYANO-ETHYLCARBAMOYL)-3-METHYL-BUTYL]AMIDE
Authors:Ward, Y.D, Thomson, D.S, Frye, L.L, Cywin, C.L, Morwick, T, Emmanuel, M.J, Zindell, R, McNeil, D, Bekkali, Y, Giradot, M, Hrapchak, M, DeTuri, M, Crane, K, White, D, Pav, S, Wang, Y, Hao, M.H, Grygon, C.A, Labadia, M.E, Freeman, D.M, Davidson, W, Hopkins, J.L, Brown, M.L, Spero, D.M.
Deposit date:2002-09-19
Release date:2003-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design and synthesis of dipeptide nitriles as reversible and potent Cathepsin S inhibitors
J.Med.Chem., 45, 2002
6XNV
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BU of 6xnv by Molmil
CRYSTAL STRUCTURE OF LISTERIA MONOCYTOGENES CBPB PROTEIN (LMO1009) IN COMPLEX WITH C-DI-AMP
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, CBS domain-containing protein
Authors:Luo, S, Tong, L.
Deposit date:2020-07-04
Release date:2020-09-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:(p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes.
Mbio, 11, 2020
2DDS
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BU of 2dds by Molmil
Crystal structure of sphingomyelinase from Bacillus cereus with cobalt ion
Descriptor: COBALT (II) ION, Sphingomyelin phosphodiesterase
Authors:Ago, H, Oda, M, Takahashi, M, Tsuge, H, Ochi, S, Katunuma, N, Miyano, M, Sakurai, J, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-02-02
Release date:2006-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of the Sphingomyelin Phosphodiesterase Activity in Neutral Sphingomyelinase from Bacillus cereus.
J.Biol.Chem., 281, 2006
5WC3
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BU of 5wc3 by Molmil
SpoIIIAG
Descriptor: SpoIIIAG, Stage III sporulation engulfment assemblyprotein
Authors:Zeytuni, N, Hong, C, Worrall, L.J, Huang, R.K, Yu, Z, Strynadka, N.C.J.
Deposit date:2017-06-29
Release date:2017-08-16
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Near-atomic resolution cryoelectron microscopy structure of the 30-fold homooligomeric SpoIIIAG channel essential to spore formation in Bacillus subtilis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6XPB
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BU of 6xpb by Molmil
Structure of human GGT1 in complex with 2-amino-4-(((1-((carboxymethyl)amino)-1-oxobutan-2-yl)oxy)(phenoxy)phosphoryl)butanoic acid (ACPB) molecule
Descriptor: 2,2-diamino-4-[(S)-({(2S)-1-[(carboxymethyl)amino]-1-oxobutan-2-yl}oxy)(hydroxy)phosphanyl]butanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Terzyan, S.S, Hanigan, M.H.
Deposit date:2020-07-08
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structures of glutathione- and inhibitor-bound human GGT1: critical interactions within the cysteinylglycine binding site.
J.Biol.Chem., 296, 2020
4ZWT
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BU of 4zwt by Molmil
Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice Type IV
Descriptor: Recombination protein uvsY
Authors:Gajewski, S, White, S.W.
Deposit date:2015-05-19
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structure and mechanism of the phage T4 recombination mediator protein UvsY.
Proc.Natl.Acad.Sci.USA, 113, 2016
5WEK
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BU of 5wek by Molmil
GluA2 bound to antagonist ZK and GSG1L in digitonin, state 1
Descriptor: Chimera of Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
Deposit date:2017-07-10
Release date:2017-08-02
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Channel opening and gating mechanism in AMPA-subtype glutamate receptors.
Nature, 549, 2017
1MTO
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BU of 1mto by Molmil
Crystal structure of a Phosphofructokinase mutant from Bacillus stearothermophilus bound with fructose-6-phosphate
Descriptor: 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructokinase
Authors:Riley-Lovingshimer, M.R, Ronning, D.R, Sacchettini, J.C, Reinhart, G.D.
Deposit date:2002-09-21
Release date:2002-12-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Reversible Ligand-Induced Dissociation of a Tryptophan-Shift Mutant of Phosphofructokinase from Bacillus stearothermophilus
Biochemistry, 41, 2002
7NE6
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BU of 7ne6 by Molmil
Human TET2 in complex with unfavourable DNA substrate.
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*AP*CP*AP*GP*GP*(5CM)P*GP*CP*CP*TP*G)-3'), ...
Authors:Rafalski, D, Bochtler, M.
Deposit date:2021-02-03
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function.
Sci Adv, 8, 2022
3VBV
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BU of 3vbv by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: 8-hydroxyquinoline-2-carboxamide, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
3VKZ
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BU of 3vkz by Molmil
3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 at atmospheric pressure
Descriptor: 3-ISOPROPYLMALIC ACID, 3-isopropylmalate dehydrogenase, CALCIUM ION, ...
Authors:Nagae, T, Watanabe, N.
Deposit date:2011-11-28
Release date:2012-02-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:High-pressure-induced water penetration into 3-isopropylmalate dehydrogenase
Acta Crystallogr.,Sect.D, 68, 2012
1VSF
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BU of 1vsf by Molmil
ASV INTEGRASE CORE DOMAIN WITH MN(II) COFACTOR AND HEPES LIGAND, HIGH MG CONCENTRATION FORM
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, INTEGRASE, MANGANESE (II) ION
Authors:Bujacz, G, Jaskolski, M, Alexandratos, J, Wlodawer, A.
Deposit date:1995-11-29
Release date:1996-04-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations.
Structure, 4, 1996
6XU4
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BU of 6xu4 by Molmil
Crystal structure of the genetically-encoded FGCaMP calcium indicator in its calcium-bound state
Descriptor: CALCIUM ION, FGCamp
Authors:Boyko, K.M, Nikolaeva, A.Y, Korzhenevskiy, D.A, Barykina, N.V, Subach, O.M, Subach, F.V.
Deposit date:2020-01-17
Release date:2020-04-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:FGCaMP7, an Improved Version of Fungi-Based Ratiometric Calcium Indicator for In Vivo Visualization of Neuronal Activity.
Int J Mol Sci, 21, 2020
5WKV
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BU of 5wkv by Molmil
Structure of an acid sensing ion channel in a resting state with calcium
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ...
Authors:Yoder, N, Gouaux, E.
Deposit date:2017-07-25
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Gating mechanisms of acid-sensing ion channels.
Nature, 555, 2018
6RLV
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BU of 6rlv by Molmil
Trypanosoma brucei Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine
Descriptor: 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine, GLYCEROL, MALONATE ION, ...
Authors:Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D.
Deposit date:2019-05-02
Release date:2020-01-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15, 2020
6XXK
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BU of 6xxk by Molmil
Crystal Structure of Human Deoxyhypusine Synthase in complex with spermidine
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, ACETATE ION, ...
Authors:Wator, E, Wilk, P, Grudnik, P.
Deposit date:2020-01-27
Release date:2020-04-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase.
Biomolecules, 10, 2020
5WPT
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BU of 5wpt by Molmil
Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed II conformation at 3.75 Angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION
Authors:Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y.
Deposit date:2017-08-07
Release date:2017-10-18
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.
Nature, 550, 2017
3VOM
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BU of 3vom by Molmil
Structure of a putative phosphoserine aminotransferase from mycobacterium tuberculosis
Descriptor: GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, Putative phosphoserine aminotransferase, ...
Authors:Coulibaly, F, Lassalle, E, Baker, H.M, Baker, E.N.
Deposit date:2012-01-30
Release date:2012-02-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of phosphoserine aminotransferase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 68, 2012
6RNN
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BU of 6rnn by Molmil
P46, an immunodominant surface protein from Mycoplasma hyopneumoniae
Descriptor: Immunoglobulin heavy chain, Immunoglobulin light chain
Authors:Guasch, A, Gonzalez-Gonzalez, L, Fita, I.
Deposit date:2019-05-09
Release date:2019-11-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of P46, an immunodominant surface protein from Mycoplasma hyopneumoniae: interaction with a monoclonal antibody.
Acta Crystallogr D Struct Biol, 76, 2020
6XJD
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BU of 6xjd by Molmil
Two mouse cGAS catalytic domain binding to human assembled nucleosome
Descriptor: Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ...
Authors:Xu, P, Li, P, Zhao, B.
Deposit date:2020-06-23
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:The molecular basis of tight nuclear tethering and inactivation of cGAS.
Nature, 587, 2020

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数据于2024-07-17公开中

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