6RLV
Trypanosoma brucei Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine
Summary for 6RLV
Entry DOI | 10.2210/pdb6rlv/pdb |
Related | 6HDZ 6HE1 6HE3 6HHV 6HHW 6HHX 6HHY 6HHZ 6HI0 |
Descriptor | Seryl-tRNA synthetase, putative, GLYCEROL, SODIUM ION, ... (6 entities in total) |
Functional Keywords | coil-coil, beta barrel, trna synthetase, inhibitor, complex, ligase |
Biological source | Trypanosoma brucei gambiense |
Total number of polymer chains | 2 |
Total formula weight | 109764.01 |
Authors | Pang, L.,De Graef, S.,Strelkov, S.V.,Weeks, S.D. (deposition date: 2019-05-02, release date: 2020-01-08, Last modification date: 2024-01-24) |
Primary citation | Pang, L.,Nautiyal, M.,De Graef, S.,Gadakh, B.,Zorzini, V.,Economou, A.,Strelkov, S.V.,Van Aerschot, A.,Weeks, S.D. Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases. Acs Chem.Biol., 15:407-415, 2020 Cited by PubMed: 31869198DOI: 10.1021/acschembio.9b00887 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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