6HHY
Klebsiella pneumoniae Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine
Summary for 6HHY
| Entry DOI | 10.2210/pdb6hhy/pdb |
| Related | 6HDZ 6HE1 6HE3 6HHV 6HHW 6HHX 6HHZ 6HI0 |
| Descriptor | Serine--tRNA ligase, 1,2-ETHANEDIOL, 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine, ... (5 entities in total) |
| Functional Keywords | coil-coil, beta barrel, trna synthetase, inhibitor, complex, ligase |
| Biological source | Klebsiella pneumoniae |
| Total number of polymer chains | 1 |
| Total formula weight | 49400.00 |
| Authors | Pang, L.,De Graef, S.,Weeks, S.D.,Strelkov, S.V. (deposition date: 2018-08-29, release date: 2019-12-18, Last modification date: 2024-01-17) |
| Primary citation | Pang, L.,Nautiyal, M.,De Graef, S.,Gadakh, B.,Zorzini, V.,Economou, A.,Strelkov, S.V.,Van Aerschot, A.,Weeks, S.D. Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases. Acs Chem.Biol., 15:407-415, 2020 Cited by PubMed: 31869198DOI: 10.1021/acschembio.9b00887 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
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