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6HHW

Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)uridine

Summary for 6HHW
Entry DOI10.2210/pdb6hhw/pdb
Related6HDZ 6HE1 6HE3 6HHV 6HHX 6HHY 6HHZ 6HI0
DescriptorAspartate--tRNA(Asp) ligase, 5'-O-(N-(L-aspartyl)-sulfamoyl)uridine (3 entities in total)
Functional Keywordsprotein-inhibitor complex, trna aminoacylation, ligase
Biological sourceThermus thermophilus
Total number of polymer chains2
Total formula weight133240.39
Authors
De Graef, S.,Pang, L.,Strelkov, S.V.,Weeks, S.D. (deposition date: 2018-08-29, release date: 2019-12-18, Last modification date: 2024-01-17)
Primary citationPang, L.,Nautiyal, M.,De Graef, S.,Gadakh, B.,Zorzini, V.,Economou, A.,Strelkov, S.V.,Van Aerschot, A.,Weeks, S.D.
Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15:407-415, 2020
Cited by
PubMed: 31869198
DOI: 10.1021/acschembio.9b00887
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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