5X2H
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![BU of 5x2h by Molmil](/molmil-images/mine/5x2h) | Crystal structure of Campylobacter jejuni Cas9 in complex with sgRNA and target DNA (AGAAACA PAM) | Descriptor: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, Non-target DNA strand, ... | Authors: | Yamada, M, Watanabe, Y, Hirano, H, Nakane, T, Ishitani, R, Nishimasu, H, Nureki, O. | Deposit date: | 2017-01-31 | Release date: | 2017-03-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems Mol. Cell, 65, 2017
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2ET8
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![BU of 2et8 by Molmil](/molmil-images/mine/2et8) | Complex Between Neamine and the 16S-RRNA A-Site | Descriptor: | (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside, 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3' | Authors: | Westhof, E. | Deposit date: | 2005-10-27 | Release date: | 2005-12-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding. Nucleic Acids Res., 33, 2005
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2XQC
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![BU of 2xqc by Molmil](/molmil-images/mine/2xqc) | DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE COMPLEXED WITH LEFT END RECOGNITION AND CLEAVAGE SITE AND ZN | Descriptor: | 5'-D(TP*TP*GP*AP*TP*GP)-3', DRA2 TRANSPOSASE LEFT END RECOGNITION SEQUENCE, TRANSPOSASE, ... | Authors: | Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F. | Deposit date: | 2010-09-01 | Release date: | 2010-10-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans. Embo J., 29, 2010
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3ZL9
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![BU of 3zl9 by Molmil](/molmil-images/mine/3zl9) | Crystal structure of the nucleocapsid protein from Schmallenberg virus | Descriptor: | NUCLEOCAPSID PROTEIN | Authors: | Ariza, A, Tanner, S.J, Walter, C.T, Dent, K.C, Shepherd, D.A, Wu, W, Matthews, S.V, Hiscox, J.A, Green, T.J, Luo, M, Elliot, R.M, Ashcroft, A.E, Stonehouse, N.J, Ranson, N.A, Barr, J.N, Edwards, T.A. | Deposit date: | 2013-01-29 | Release date: | 2013-05-01 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Nucleocapsid Protein Structures from Orthobunyaviruses Reveal Insight Into Ribonucleoprotein Architecture and RNA Polymerization. Nucleic Acids Res., 41, 2013
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2ET3
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![BU of 2et3 by Molmil](/molmil-images/mine/2et3) | Complex Between Gentamicin C1A and the 16S-RRNA A-Site | Descriptor: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3' | Authors: | Westhof, E. | Deposit date: | 2005-10-27 | Release date: | 2005-12-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding. Nucleic Acids Res., 33, 2005
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4NRO
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![BU of 4nro by Molmil](/molmil-images/mine/4nro) | |
4NRQ
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![BU of 4nrq by Molmil](/molmil-images/mine/4nrq) | Crystal structure of human ALKBH5 in complex with pyridine-2,4-dicarboxylate | Descriptor: | MANGANESE (II) ION, PYRIDINE-2,4-DICARBOXYLIC ACID, RNA demethylase ALKBH5 | Authors: | Feng, C, Chen, Z, Liu, Y. | Deposit date: | 2013-11-27 | Release date: | 2014-03-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition J.Biol.Chem., 289, 2014
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3HJF
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![BU of 3hjf by Molmil](/molmil-images/mine/3hjf) | Crystal structure of T. thermophilus Argonaute E546 mutant protein complexed with DNA guide strand and 15-nt RNA target strand | Descriptor: | 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', 5'-R(*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', Argonaute, ... | Authors: | Wang, Y, Li, H, Sheng, G, Patel, D.J. | Deposit date: | 2009-05-21 | Release date: | 2009-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.056 Å) | Cite: | Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. Nature, 461, 2009
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4E6B
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![BU of 4e6b by Molmil](/molmil-images/mine/4e6b) | |
1IQV
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![BU of 1iqv by Molmil](/molmil-images/mine/1iqv) | |
3ER9
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![BU of 3er9 by Molmil](/molmil-images/mine/3er9) | Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase complex with UU and 3'-deoxy ATP | Descriptor: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-R(UP*U)-3', CALCIUM ION, ... | Authors: | Li, C, Li, H, Zhou, S, Poulos, T.L, Gershon, P.D. | Deposit date: | 2008-10-01 | Release date: | 2009-06-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase Structure, 17, 2009
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4NGD
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![BU of 4ngd by Molmil](/molmil-images/mine/4ngd) | Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 12-mer siRNA having 5'-p and UU-3' ends (1.95 Angstrom resolution) | Descriptor: | 5'-R(P*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', DI(HYDROXYETHYL)ETHER, Endoribonuclease Dicer, ... | Authors: | Tian, Y, Simanshu, D.K, Patel, D.J. | Deposit date: | 2013-11-01 | Release date: | 2014-03-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.958 Å) | Cite: | A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer. Mol.Cell, 53, 2014
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4NHA
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![BU of 4nha by Molmil](/molmil-images/mine/4nha) | Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 16-mer siRNA having 5'-p and UU-3' ends (3.4 Angstrom resolution) | Descriptor: | 5'-R(P*GP*CP*GP*UP*UP*GP*GP*CP*CP*AP*AP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer | Authors: | Simanshu, D.K, Tian, Y, Ma, J.-B, Patel, D.J. | Deposit date: | 2013-11-04 | Release date: | 2014-03-05 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (3.401 Å) | Cite: | A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer. Mol.Cell, 53, 2014
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4NH5
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![BU of 4nh5 by Molmil](/molmil-images/mine/4nh5) | |
4NGG
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![BU of 4ngg by Molmil](/molmil-images/mine/4ngg) | |
6WC5
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![BU of 6wc5 by Molmil](/molmil-images/mine/6wc5) | Crystal Structure of a Ternary MEF2B/NKX2-5/myocardin enhancer DNA Complex | Descriptor: | Homeobox protein Nkx-2.5, Myocardin enhancer DNA, Myocyte-specific enhancer factor 2B | Authors: | Chen, L, Lei, X. | Deposit date: | 2020-03-29 | Release date: | 2020-07-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface. J.Mol.Biol., 432, 2020
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4NGB
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![BU of 4ngb by Molmil](/molmil-images/mine/4ngb) | |
4NH3
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![BU of 4nh3 by Molmil](/molmil-images/mine/4nh3) | |
3AQK
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![BU of 3aqk by Molmil](/molmil-images/mine/3aqk) | |
1XV6
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![BU of 1xv6 by Molmil](/molmil-images/mine/1xv6) | |
6WC2
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![BU of 6wc2 by Molmil](/molmil-images/mine/6wc2) | Crystal Structure of a Ternary MEF2 Chimera/NKX2-5/myocardin enhancer DNA Complex | Descriptor: | Homeobox protein Nkx-2.5, MEF2 Chimera,Myocyte-specific enhancer factor 2B,Myocyte-specific enhancer factor 2A, Myocardin Enhancer DNA | Authors: | Lei, X, Chen, L. | Deposit date: | 2020-03-29 | Release date: | 2020-07-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface. J.Mol.Biol., 432, 2020
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3AQN
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![BU of 3aqn by Molmil](/molmil-images/mine/3aqn) | |
4HDH
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![BU of 4hdh by Molmil](/molmil-images/mine/4hdh) | Crystal Structure of viral RdRp in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Polyprotein, ZINC ION | Authors: | Surana, P, Nair, D.T. | Deposit date: | 2012-10-02 | Release date: | 2013-12-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state. Nucleic Acids Res., 42, 2014
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3AQL
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![BU of 3aql by Molmil](/molmil-images/mine/3aql) | |
3AQM
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![BU of 3aqm by Molmil](/molmil-images/mine/3aqm) | Structure of bacterial protein (form II) | Descriptor: | MAGNESIUM ION, Poly(A) polymerase | Authors: | Toh, Y, Takeshita, D, Tomita , K. | Deposit date: | 2010-11-09 | Release date: | 2011-02-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Mechanism for the alteration of the substrate specificities of template-independent RNA polymerases Structure, 19, 2011
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