5X2H
Crystal structure of Campylobacter jejuni Cas9 in complex with sgRNA and target DNA (AGAAACA PAM)
Summary for 5X2H
Entry DOI | 10.2210/pdb5x2h/pdb |
Related | 5X2G |
Descriptor | CRISPR-associated endonuclease Cas9, sgRNA, Target DNA strand, ... (6 entities in total) |
Functional Keywords | crispr-cas9, rna, dna, complex, nuclease, hydrolase-rna-dna complex, hydrolase/rna/dna |
Biological source | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) More |
Total number of polymer chains | 4 |
Total formula weight | 137822.21 |
Authors | Yamada, M.,Watanabe, Y.,Hirano, H.,Nakane, T.,Ishitani, R.,Nishimasu, H.,Nureki, O. (deposition date: 2017-01-31, release date: 2017-03-29, Last modification date: 2024-03-27) |
Primary citation | Yamada, M.,Watanabe, Y.,Gootenberg, J.S.,Hirano, H.,Ran, F.A.,Nakane, T.,Ishitani, R.,Zhang, F.,Nishimasu, H.,Nureki, O. Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems Mol. Cell, 65:1109-1121.e3, 2017 Cited by PubMed: 28306506DOI: 10.1016/j.molcel.2017.02.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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