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7U8J	Crystal structure of chimeric hemagglutinin cH4/3 in complex with broad protective antibody 31.a.83 Descriptor: Antibody Fab light chain, Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, ... Authors: Zhu, X, Wilson, I.A. Deposit date: 2022-03-08 Release date: 2022-06-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (4.9 Å) Cite: Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface. Proc.Natl.Acad.Sci.USA, 119, 2022
7TZ5	Cryo-EM structure of antibody TJ5-5 bound to H3 COBRA TJ5 hemagglutinin Descriptor: Hemagglutinin, TJ5-5 heavy chain, TJ5-5 light chain Authors: Abbadi, N.S, Mousa, J.J. Deposit date: 2022-02-15 Release date: 2022-07-06 Last modified: 2022-09-21 Method: ELECTRON MICROSCOPY (3.41 Å) Cite: Differential Recognition of Computationally Optimized H3 Hemagglutinin Influenza Vaccine Candidates by Human Antibodies. J.Virol., 96, 2022
7TRI	Human antibody S8V1-172 in complex with the influenza hemagglutinin head domain of A/Sydney/05/1997(H3N2) Descriptor: Hemagglutinin, S8V1-172 Fab heavy chain, S8V1-172 Fab kappa light chain, ... Authors: McCarthy, K.R. Deposit date: 2022-01-28 Release date: 2023-08-02 Last modified: 2024-01-03 Method: X-RAY DIFFRACTION (3.6 Å) Cite: A new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses. Plos Biol., 21, 2023
7TRH	Human antibody K03.28 in complex with the influenza hemagglutinin head domain of A/California/07/2009(H1N1)(X-181) Descriptor: Hemagglutinin, K03.28 Fab heavy chain, K03.28 Fab lambda light chain Authors: McCarthy, K.R. Deposit date: 2022-01-28 Release date: 2023-08-02 Last modified: 2024-01-03 Method: X-RAY DIFFRACTION (3 Å) Cite: A new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses. Plos Biol., 21, 2023
7T3D	CryoEM map of anchor 222-1C06 Fab and lateral patch 2B05 Fab binding H1 HA Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 222-1C06 mAb heavy chain, ... Authors: Han, J, Ward, A.B. Deposit date: 2021-12-07 Release date: 2022-01-12 Last modified: 2022-03-30 Method: ELECTRON MICROSCOPY (3.38 Å) Cite: Broadly neutralizing antibodies target a haemagglutinin anchor epitope. Nature, 602, 2022
7T1V	Crystal structure of an equine H7 hemagglutinin from A/equine/NY/49/73 (H7N7) in complex with 3'-GcLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Zhu, X, Wilson, I.A. Deposit date: 2021-12-02 Release date: 2022-01-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.05 Å) Cite: N -Glycolylneuraminic Acid Binding of Avian and Equine H7 Influenza A Viruses. J.Virol., 96, 2022
7SCO	Structure of H1 influenza hemagglutinin bound to Fab 310-39G10 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 310-39G10 Fab, ... Authors: Torrents de la Pena, A, Ward, A.B. Deposit date: 2021-09-28 Release date: 2022-08-24 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (3.37 Å) Cite: Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus. Immunity, 55, 2022
7SCN	Structure of H1 NC99 influenza hemagglutinin bound to Fab 310-63E6 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 310-63E6 Fab, Heavy Chain, ... Authors: Ward, A, Torrents de la Pena, A. Deposit date: 2021-09-28 Release date: 2022-08-24 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (3.02 Å) Cite: Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus. Immunity, 55, 2022
7RDH	Crystal structure of the de novo designed binding protein H3mb in complex with the 1968 influenza A virus hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, De novo designed protein H3mb, ... Authors: Kadam, R.U, Wilson, I.A. Deposit date: 2021-07-09 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Design of protein-binding proteins from the target structure alone. Nature, 605, 2022
7RCR	Crystal Structure of the refolded Hemagglutinin head domain of Influenza A virus A/Ohio/09/2015 Descriptor: 1,2-ETHANEDIOL, Hemagglutinin Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-07-08 Release date: 2021-08-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal Structure of the refolded Hemagglutinin head domain of Influenzavirus A Influenza A virus A/Ohio/09/2015 to be published
7QA4	Crystal structure of stabilized H3N2 A/Hong Kong/1/1968 Hemagglutinin at 2.2 Angstrom Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Milder, F.J, Langedijk, J.P.M. Deposit date: 2021-11-16 Release date: 2022-02-02 Last modified: 2022-03-30 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions. Proc.Natl.Acad.Sci.USA, 119, 2022
7MFG	Cryo-EM structure of the VRC310 clinical trial, vaccine-elicited, human antibody 310-030-1D06 Fab in complex with an H1 NC99 HA trimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 310-030-1D06 Heavy, 310-030-1D06 Light, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2021-04-09 Release date: 2021-11-03 Last modified: 2022-03-09 Method: ELECTRON MICROSCOPY (3.87 Å) Cite: A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination. Nat Med, 28, 2022
7MEM	CryoEM structure of monoclonal Fab 045-09 2B05 binding the lateral patch of influenza virus H1 HA Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of monoclonal antibody 045-09 2B05, ... Authors: Han, J, Ward, A. Deposit date: 2021-04-06 Release date: 2021-07-28 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes. Sci Transl Med, 13, 2021
7L0L	Cryo-EM structure of the VRC316 clinical trial, vaccine-elicited, human antibody 316-310-1B11 in complex with an H2 CAN05 HA trimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 316-310-1B11 Heavy Chain, 316-310-1B11 Light Chain, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2020-12-11 Release date: 2021-11-03 Last modified: 2022-03-09 Method: ELECTRON MICROSCOPY (2.85 Å) Cite: A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination. Nat Med, 28, 2022
7KQI	Antibodies that engage the hemagglutinin receptor-binding site of influenza B viruses Descriptor: 1209 Fab heavy chain, 1209 Fab light chain, Hemagglutinin, ... Authors: Bajic, G, Harrison, S.C. Deposit date: 2020-11-16 Release date: 2020-12-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (4.2 Å) Cite: Antibodies That Engage the Hemagglutinin Receptor-Binding Site of Influenza B Viruses. Acs Infect Dis., 7, 2021
7KQH	Antibodies that engage the hemagglutinin receptor-binding site of influenza B viruses Descriptor: 2365 Fab heavy chain, 2365 Fab light chain, Hemagglutinin, ... Authors: Bajic, G, Harrison, S.C. Deposit date: 2020-11-16 Release date: 2020-12-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Antibodies That Engage the Hemagglutinin Receptor-Binding Site of Influenza B Viruses. Acs Infect Dis., 7, 2021
7KQG	Antibodies that engage the hemagglutinin receptor-binding site of influenza B viruses Descriptor: 1272 Fab heavy chain, 1272 Fab light chain, Hemagglutinin, ... Authors: Bajic, G, Harrison, S.C. Deposit date: 2020-11-16 Release date: 2020-12-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Antibodies That Engage the Hemagglutinin Receptor-Binding Site of Influenza B Viruses. Acs Infect Dis., 7, 2021
7KNA	Localized reconstruction of the H1 A/Michigan/45/2015 ectodomain displayed at the surface of I53_dn5 nanoparticle Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin,I53_dn5 Authors: Acton, O.J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-11-04 Release date: 2021-03-31 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Quadrivalent influenza nanoparticle vaccines induce broad protection. Nature, 592, 2021
7KC1	Cryo-EM structure of SRR2899884.46167H+MEDI8852L fab in complex with Victoria HA Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2020-10-04 Release date: 2021-05-12 Last modified: 2021-07-14 Method: ELECTRON MICROSCOPY (3.41 Å) Cite: Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses. Front Immunol, 12, 2021
7K3B	Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation C, central helices splay Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Gui, M, Gao, J, Xiang, Y. Deposit date: 2020-09-10 Release date: 2020-11-11 Last modified: 2020-12-09 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural intermediates in the low pH-induced transition of influenza hemagglutinin. Plos Pathog., 16, 2020
7K3A	Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation B, fusion peptide release Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Gui, M, Gao, J, Xiang, Y. Deposit date: 2020-09-10 Release date: 2020-11-11 Last modified: 2020-12-09 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural intermediates in the low pH-induced transition of influenza hemagglutinin. Plos Pathog., 16, 2020
7K39	Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation A, neutral pH-like Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Gui, M, Gao, J, Xiang, Y. Deposit date: 2020-09-10 Release date: 2020-11-11 Last modified: 2020-12-09 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural intermediates in the low pH-induced transition of influenza hemagglutinin. Plos Pathog., 16, 2020
7K37	Structure of full-length influenza HA with a head-binding antibody at pH 7.8 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Gui, M, Xiang, Y, Gao, J. Deposit date: 2020-09-10 Release date: 2020-11-11 Last modified: 2020-12-09 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural intermediates in the low pH-induced transition of influenza hemagglutinin. Plos Pathog., 16, 2020
7JPD	Crystal structure of the trimeric full length mature hemagglutinin from influenza A virus A/Fort Monmouth/1/1947 Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-08-07 Release date: 2021-10-06 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structural characterisation of hemagglutinin from seven Influenza A H1N1 strains reveal diversity in the C05 antibody recognition site. Sci Rep, 13, 2023
7JP4	Crystal structure of a refolded head domain hemagglutinin HA from Influenza A virus A/Fort Monmouth/1/1947 Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Hemagglutinin Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-08-07 Release date: 2021-01-27 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural characterisation of hemagglutinin from seven Influenza A H1N1 strains reveal diversity in the C05 antibody recognition site. Sci Rep, 13, 2023

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