7KNA

Localized reconstruction of the H1 A/Michigan/45/2015 ectodomain displayed at the surface of I53_dn5 nanoparticle

Summary for 7KNA

• Entry DOI: 10.2210/pdb7kna/pdb
• EMDB information: 22937
• Descriptor: Hemagglutinin,I53_dn5, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: hemagglutinin, fusion protein, neutralizing antibodies, vaccine, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein
• Biological source: Influenza A virus; More
• Total number of polymer chains: 3
• Total formula weight: 222258.99

Authors

Acton, O.J.,Park, Y.J.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2020-11-04, release date: 2021-03-31, Last modification date: 2021-05-05)

• Primary citation: Boyoglu-Barnum, S.,Ellis, D.,Gillespie, R.A.,Hutchinson, G.B.,Park, Y.J.,Moin, S.M.,Acton, O.J.,Ravichandran, R.,Murphy, M.,Pettie, D.,Matheson, N.,Carter, L.,Creanga, A.,Watson, M.J.,Kephart, S.,Ataca, S.,Vaile, J.R.,Ueda, G.,Crank, M.C.,Stewart, L.,Lee, K.K.,Guttman, M.,Baker, D.,Mascola, J.R.,Veesler, D.,Graham, B.S.,King, N.P.,Kanekiyo, M.; Quadrivalent influenza nanoparticle vaccines induce broad protection.; Nature, 592:623-628, 2021; PubMed: 33762730; DOI: 10.1038/s41586-021-03365-x

Experimental method

ELECTRON MICROSCOPY (3.3 Å)