7TRI

Human antibody S8V1-172 in complex with the influenza hemagglutinin head domain of A/Sydney/05/1997(H3N2)

Summary for 7TRI

Entry DOI	10.2210/pdb7tri/pdb
Descriptor	Hemagglutinin, S8V1-172 Fab kappa light chain, S8V1-172 Fab heavy chain, ... (4 entities in total)
Functional Keywords	influenza, antibody, neutralizing, immune system, immune system-viral protein complex, immune system/viral protein
Biological source	Influenza A virus (A/Sydney/5/1997(H3N2)) More
Total number of polymer chains	3
Total formula weight	82911.43
Authors	McCarthy, K.R. (deposition date: 2022-01-28, release date: 2023-08-02, Last modification date: 2024-01-03)
Primary citation	Simmons, H.C.,Watanabe, A.,Oguin Iii, T.H.,Van Itallie, E.S.,Wiehe, K.J.,Sempowski, G.D.,Kuraoka, M.,Kelsoe, G.,McCarthy, K.R. A new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses. Plos Biol., 21:e3002415-e3002415, 2023 Cited by PubMed: 38127922 DOI: 10.1371/journal.pbio.3002415 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.6 Å)

Structure validation