3EF9
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![BU of 3ef9 by Molmil](/molmil-images/mine/3ef9) | Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability | Descriptor: | SULFATE ION, Thymidylate synthase | Authors: | Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H. | Deposit date: | 2008-09-08 | Release date: | 2010-03-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability . Biochemistry, 49, 2010
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3EGH
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![BU of 3egh by Molmil](/molmil-images/mine/3egh) | Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1), the PP1 binding and PDZ domains of Spinophilin and the small natural molecular toxin Nodularin-R | Descriptor: | GLYCEROL, MANGANESE (II) ION, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, ... | Authors: | Ragusa, M.J, Page, R, Peti, W. | Deposit date: | 2008-09-10 | Release date: | 2010-03-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites. Nat.Struct.Mol.Biol., 17, 2010
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3NTD
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![BU of 3ntd by Molmil](/molmil-images/mine/3ntd) | Structure of the Shewanella loihica PV-4 NADH-dependent persulfide reductase C531S Mutant | Descriptor: | CHLORIDE ION, COENZYME A, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, ... | Authors: | Sazinsky, M.H, Warner, M.D, Lukose, V, Lee, K.H, Crane, E.J. | Deposit date: | 2010-07-03 | Release date: | 2010-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Characterization of an NADH-Dependent Persulfide Reductase from Shewanella loihica PV-4: Implications for the Mechanism of Sulfur Respiration via FAD-Dependent Enzymes . Biochemistry, 50, 2010
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3EPB
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![BU of 3epb by Molmil](/molmil-images/mine/3epb) | Human AdoMetDC E256Q mutant complexed with putrescine | Descriptor: | 1,4-DIAMINOBUTANE, PYRUVIC ACID, S-adenosylmethionine decarboxylase alpha chain, ... | Authors: | Bale, S, Lopez, M.M, Makhatadze, G.I, Fang, Q, Pegg, A.E, Ealick, S.E. | Deposit date: | 2008-09-29 | Release date: | 2008-12-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase. Biochemistry, 47, 2008
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4MCB
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![BU of 4mcb by Molmil](/molmil-images/mine/4mcb) | H.influenzae TrmD in complex with N-(4-{[(1H-IMIDAZOL-2-YLMETHYL)AMINO]METHYL}BENZYL)-4-OXO-3,4-DIHYDROTHIENO[2,3-D]PYRIMIDINE-5-CARBOXAMIDE | Descriptor: | ACETATE ION, GLYCEROL, N-(4-{[(1H-imidazol-2-ylmethyl)amino]methyl}benzyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-5-carboxamide, ... | Authors: | Olivier, N.B, Hill, P. | Deposit date: | 2013-08-21 | Release date: | 2013-09-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Selective Inhibitors of Bacterial t-RNA-(N(1)G37) Methyltransferase (TrmD) That Demonstrate Novel Ordering of the Lid Domain. J.Med.Chem., 56, 2013
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3EPP
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![BU of 3epp by Molmil](/molmil-images/mine/3epp) | Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin | Descriptor: | SINEFUNGIN, mRNA cap guanine-N7 methyltransferase | Authors: | Amaya, M.F, Zeng, H, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Plotnikov, A.N, Wu, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-09-29 | Release date: | 2008-10-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin. To be Published
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2IG7
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![BU of 2ig7 by Molmil](/molmil-images/mine/2ig7) | Crystal structure of Human Choline Kinase B | Descriptor: | Choline/ethanolamine kinase, UNKNOWN ATOM OR ION | Authors: | Rabeh, W.M, Tempel, W, Nedyalkova, L, Wasney, G, Landry, R, Vedadi, M, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2006-09-22 | Release date: | 2006-10-10 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of Human Choline Kinase B To be Published
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3EQD
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![BU of 3eqd by Molmil](/molmil-images/mine/3eqd) | |
3NY0
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![BU of 3ny0 by Molmil](/molmil-images/mine/3ny0) | Crystal Structure of UreE from Helicobacter pylori (Ni2+ bound form) | Descriptor: | NICKEL (II) ION, Urease accessory protein ureE | Authors: | Shi, R, Munger, C, Assinas, A, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2010-07-14 | Release date: | 2010-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Crystal Structures of Apo and Metal-Bound Forms of the UreE Protein from Helicobacter pylori: Role of Multiple Metal Binding Sites Biochemistry, 49, 2010
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3EJQ
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![BU of 3ejq by Molmil](/molmil-images/mine/3ejq) | Golgi alpha-Mannosidase II in complex with 5-substitued swainsonine analog: (5R)-5-[2'-oxo-2'-(4-methylphenyl)ethyl]-swainsonine | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1-(4-methylphenyl)-2-[(1S,2R,5R,8R,8aR)-1,2,8-trihydroxyoctahydroindolizin-5-yl]ethanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kuntz, D.A, Rose, D.R. | Deposit date: | 2008-09-18 | Release date: | 2009-10-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural Investigation of the Binding of 5-Substituted Swainsonine Analogues to Golgi alpha-Mannosidase II. Chembiochem, 11, 2010
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3NWM
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![BU of 3nwm by Molmil](/molmil-images/mine/3nwm) | Crystal structure of a single chain construct composed of MHC class I H-2Kd, beta-2microglobulin and a peptide which is an autoantigen for type 1 diabetes | Descriptor: | Peptide/beta-2microglobulin/MHC class I H-2Kd chimeric protein | Authors: | Ramagopal, U.A, Samanta, D, Nathenson, S.G, Almo, S.C. | Deposit date: | 2010-07-09 | Release date: | 2011-07-06 | Last modified: | 2017-06-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells. Proc.Natl.Acad.Sci.USA, 108, 2011
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4HIM
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![BU of 4him by Molmil](/molmil-images/mine/4him) | |
4HJ3
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![BU of 4hj3 by Molmil](/molmil-images/mine/4hj3) | |
3EKW
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![BU of 3ekw by Molmil](/molmil-images/mine/3ekw) | Crystal structure of the inhibitor Atazanavir (ATV) in complex with a multi-drug resistance HIV-1 protease variant (L10I/G48V/I54V/V64I/V82A) Refer: FLAP+ in citation. | Descriptor: | (3S,8S,9S,12S)-3,12-BIS(1,1-DIMETHYLETHYL)-8-HYDROXY-4,11-DIOXO-9-(PHENYLMETHYL)-6-[[4-(2-PYRIDINYL)PHENYL]METHYL]-2,5, 6,10,13-PENTAAZATETRADECANEDIOIC ACID DIMETHYL ESTER, PHOSPHATE ION, ... | Authors: | Prabu-Jeyabalan, M, King, N.M, Bandaranayake, R.M. | Deposit date: | 2008-09-19 | Release date: | 2009-09-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Extreme Entropy-Enthalpy Compensation in a Drug-Resistant Variant of HIV-1 Protease. Acs Chem.Biol., 7, 2012
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3ESW
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![BU of 3esw by Molmil](/molmil-images/mine/3esw) | Complex of yeast PNGase with GlcNAc2-IAc. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase, UV excision repair protein RAD23, ... | Authors: | Zhao, G, Zhou, X, Lennarz, W.J, Schindelin, H. | Deposit date: | 2008-10-06 | Release date: | 2008-11-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural and mutational studies on the importance of oligosaccharide binding for the activity of yeast PNGase. Glycobiology, 19, 2009
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4HJW
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![BU of 4hjw by Molmil](/molmil-images/mine/4hjw) | Crystal structure of Metarhizium anisopliae IDCase in apo form | Descriptor: | Uracil-5-carboxylate decarboxylase, ZINC ION | Authors: | Xu, S, Zhu, J, Ding, J. | Deposit date: | 2012-10-14 | Release date: | 2013-09-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase. Cell Res., 23, 2013
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3E2S
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![BU of 3e2s by Molmil](/molmil-images/mine/3e2s) | Crystal Structure Reduced PutA86-630 Mutant Y540S Complexed with L-proline | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, PROLINE, ... | Authors: | Tanner, J.J. | Deposit date: | 2008-08-06 | Release date: | 2009-02-03 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A conserved active site tyrosine residue of proline dehydrogenase helps enforce the preference for proline over hydroxyproline as the substrate. Biochemistry, 48, 2009
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3EMG
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![BU of 3emg by Molmil](/molmil-images/mine/3emg) | |
4HM6
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4MK7
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![BU of 4mk7 by Molmil](/molmil-images/mine/4mk7) | |
4HM8
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![BU of 4hm8 by Molmil](/molmil-images/mine/4hm8) | |
3O15
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![BU of 3o15 by Molmil](/molmil-images/mine/3o15) | Crystal Structure of Bacillus subtilis Thiamin Phosphate Synthase Complexed with a Carboxylated Thiazole Phosphate | Descriptor: | 2-TRIFLUOROMETHYL-5-METHYLENE-5H-PYRIMIDIN-4-YLIDENEAMINE, 4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazole-2-carboxylic acid, PYROPHOSPHATE 2-, ... | Authors: | McCulloch, K.M, Hanes, J.W, Abdelwahed, S, Mahanta, N, Hazra, A, Ishida, K, Begley, T.P, Ealick, S.E. | Deposit date: | 2010-07-20 | Release date: | 2011-07-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure and Kinetic Characterization of Bacillus subtilis
Thiamin Phosphate Synthase with a Carboxylated Thiazole Phosphate to be published
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4HO4
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![BU of 4ho4 by Molmil](/molmil-images/mine/4ho4) | Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with thymidine and glucose-1-phosphate | Descriptor: | 1-O-phosphono-alpha-D-glucopyranose, Glucose-1-phosphate thymidylyltransferase, SULFATE ION, ... | Authors: | Chen, T.J, Chien, W.T, Lin, C.C, Wang, W.C. | Deposit date: | 2012-10-22 | Release date: | 2013-10-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with thymidine and glucose-1-phosphate TO BE PUBLISHED
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3O21
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![BU of 3o21 by Molmil](/molmil-images/mine/3o21) | High resolution structure of GluA3 N-terminal domain (NTD) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 3, PHOSPHATE ION | Authors: | Rossmann, M, Sukumaran, M, Penn, A.C, Veprintsev, D.B, Babu, M.M, Jensen, M.H, Greger, I.H. | Deposit date: | 2010-07-22 | Release date: | 2011-03-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Dynamics and allosteric potential of the AMPA receptor N-terminal domain Embo J., 30, 2011
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3E24
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![BU of 3e24 by Molmil](/molmil-images/mine/3e24) | |