3EPB
Human AdoMetDC E256Q mutant complexed with putrescine
Summary for 3EPB
Entry DOI | 10.2210/pdb3epb/pdb |
Related | 1I72 1I79 1I7B 1I7C 1I7M 1JEN 3EP3 3EP4 3EP5 3EP6 3EP7 3EP8 3EP9 3EPA |
Descriptor | S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, 1,4-DIAMINOBUTANE, ... (5 entities in total) |
Functional Keywords | adometdc with mutation in putrescine binding site, decarboxylase, lyase, pyruvate, s-adenosyl-l-methionine, spermidine biosynthesis, zymogen |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 37758.02 |
Authors | Bale, S.,Lopez, M.M.,Makhatadze, G.I.,Fang, Q.,Pegg, A.E.,Ealick, S.E. (deposition date: 2008-09-29, release date: 2008-12-23, Last modification date: 2023-11-15) |
Primary citation | Bale, S.,Lopez, M.M.,Makhatadze, G.I.,Fang, Q.,Pegg, A.E.,Ealick, S.E. Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase. Biochemistry, 47:13404-13417, 2008 Cited by PubMed: 19053272DOI: 10.1021/bi801732m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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