3O15

Crystal Structure of Bacillus subtilis Thiamin Phosphate Synthase Complexed with a Carboxylated Thiazole Phosphate

Summary for 3O15

• Entry DOI: 10.2210/pdb3o15/pdb
• Related: 3O16
• Descriptor: Thiamine-phosphate pyrophosphorylase, 4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazole-2-carboxylic acid, 2-TRIFLUOROMETHYL-5-METHYLENE-5H-PYRIMIDIN-4-YLIDENEAMINE, ... (5 entities in total)
• Functional Keywords: thiamin biosynthesis, tim barrel, protein-intermediate complex, transferase
• Biological source: Bacillus subtilis
• Total number of polymer chains: 1
• Total formula weight: 25916.02

Authors

McCulloch, K.M.,Hanes, J.W.,Abdelwahed, S.,Mahanta, N.,Hazra, A.,Ishida, K.,Begley, T.P.,Ealick, S.E. (deposition date: 2010-07-20, release date: 2011-07-27, Last modification date: 2024-02-21)

• Primary citation: McCulloch, K.M.,Hanes, J.W.,Abdelwahed, S.,Mahanta, N.,Hazra, A.,Ishida, K.,Begley, T.P.,Ealick, S.E.; Crystal Structure and Kinetic Characterization of Bacillus subtilis Thiamin Phosphate Synthase with a Carboxylated Thiazole Phosphate; to be published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)