3NWM

Crystal structure of a single chain construct composed of MHC class I H-2Kd, beta-2microglobulin and a peptide which is an autoantigen for type 1 diabetes

Summary for 3NWM

Entry DOI	10.2210/pdb3nwm/pdb
Related	1VGK
Descriptor	Peptide/beta-2microglobulin/MHC class I H-2Kd chimeric protein (2 entities in total)
Functional Keywords	mhc class i, h-2kd, peptide-mhc complex, immunoglobulin fold, immune system
Biological source	Mus musculus (mouse) More
Total number of polymer chains	1
Total formula weight	49659.17
Authors	Ramagopal, U.A.,Samanta, D.,Nathenson, S.G.,Almo, S.C. (deposition date: 2010-07-09, release date: 2011-07-06, Last modification date: 2017-06-28)
Primary citation	Samanta, D.,Mukherjee, G.,Ramagopal, U.A.,Chaparro, R.J.,Nathenson, S.G.,DiLorenzo, T.P.,Almo, S.C. Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells. Proc.Natl.Acad.Sci.USA, 108:13682-13687, 2011 Cited by PubMed: 21825122 DOI: 10.1073/pnas.1110971108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation