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3NWM

Crystal structure of a single chain construct composed of MHC class I H-2Kd, beta-2microglobulin and a peptide which is an autoantigen for type 1 diabetes

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Peptide/beta-2microglobulin/MHC class I H-2Kd chimeric proteinpolymer44349659.21UniProt (Q91XJ8)
UniProt (Q5KTQ2)
Pfam (PF07654)
Pfam (PF00129)
UniProt (by SIFTS) (P01887)
UniProt (by SIFTS) (P01902)
Mus musculus (mouse)
2B
(A)
waterwater18.014Chemie (HOH)
Sequence modifications
A: 1 - 9 (PDB: 3NWM)
PDBExternal DatabaseDetails
Met 0-expression tag
Gly 10-linker
Gly 11-linker
Gly 12-linker
Ala 13-linker
Ser 14-linker
Gly 15-linker
Gly 16-linker
Gly 17-linker
Gly 18-linker
Ser 19-linker
Gly 20-linker
Gly 21-linker
Gly 22-linker
Gly 23-linker
Ser -1-linker
A: 1 - 99 (UniProt: Q91XJ8)
PDBExternal DatabaseDetails
Met 0-expression tag
Gly 100-linker
Gly 101-linker
Gly 102-linker
Gly 103-linker
Ser 104-linker
Gly 105-linker
Gly 106-linker
Gly 107-linker
Gly 108-linker
Ser 109-linker
Gly 110-linker
Gly 111-linker
Gly 112-linker
Gly 113-linker
Ser 114-linker
Gly 115-linker
Gly 116-linker
Gly 117-linker
Gly 118-linker
Ser 119-linker
Gly 1-linker
A: 2 - 274 (UniProt: Q5KTQ2)
PDBExternal DatabaseDetails
Ala 275-expression tag
Ala 276-expression tag
Ala 277-expression tag
Gly 278-expression tag
Gly 279-expression tag
Thr 280-expression tag
Gly 281-expression tag
Gly 282-expression tag
Leu 283-expression tag
Asn 284-expression tag
Asp 285-expression tag
Ile 286-expression tag
Phe 287-expression tag
Glu 288-expression tag
Ala 289-expression tag
Gln 290-expression tag
Lys 291-expression tag
Ile 292-expression tag
Glu 293-expression tag
Trp 294-expression tag
His 295-expression tag
Glu 296-expression tag
Gly 297-expression tag
Leu 298-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight49659.2
All*Total formula weight49659.2
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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