3EPP
Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin
Summary for 3EPP
Entry DOI | 10.2210/pdb3epp/pdb |
Related | 3BGV |
Descriptor | mRNA cap guanine-N7 methyltransferase, SINEFUNGIN (3 entities in total) |
Functional Keywords | mrna cap guanine-n7 methyltransferase, rnmt, sinefungin, structural genomics, structural genomics consortium, sgc, mrna capping, mrna processing, nucleus, phosphoprotein, rna-binding, s-adenosyl-l-methionine, transferase |
Biological source | Homo sapiens |
Cellular location | Nucleus : O43148 |
Total number of polymer chains | 2 |
Total formula weight | 74309.20 |
Authors | Amaya, M.F.,Zeng, H.,Loppnau, P.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Botchkarev, A.,Min, J.,Plotnikov, A.N.,Wu, H.,Structural Genomics Consortium (SGC) (deposition date: 2008-09-29, release date: 2008-10-21, Last modification date: 2024-02-21) |
Primary citation | Zeng, H.,Amaya, M.F.,Loppnau, P.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Botchkarev, A.,Min, J.,Plotnikov, A.N.,Wu, H. Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin. To be Published, |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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