3EPP
Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | mRNA cap guanine-N7 methyltransferase | polymer | 313 | 36773.2 | 2 | UniProt (O43148) Pfam (PF03291) | Homo sapiens | mRNA (guanine-N(7)-)-methyltransferase, RG7MT1, mRNA cap methyltransferase, hcm1p, hCMT1, hMet |
| 2 | C, D (A, B) | SINEFUNGIN | non-polymer | 381.4 | 2 | Chemie (SFG) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 313 (UniProt: O43148)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73546.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 762.8 | |
| All* | Total formula weight | 74309.2 |
