3EPP
Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE SFG A 401 |
| Chain | Residue |
| A | LYS17 |
| A | PHE122 |
| A | VAL123 |
| A | TYR126 |
| A | MET137 |
| A | HOH427 |
| A | HOH444 |
| A | GLY42 |
| A | GLY44 |
| A | ASP64 |
| A | ILE65 |
| A | ASP98 |
| A | SER99 |
| A | SER100 |
| A | GLN121 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE SFG B 401 |
| Chain | Residue |
| B | LYS17 |
| B | GLY42 |
| B | GLY44 |
| B | ASP64 |
| B | ILE65 |
| B | ASP98 |
| B | SER99 |
| B | GLN121 |
| B | PHE122 |
| B | VAL123 |
| B | TYR126 |
| B | MET137 |
| B | HOH430 |
| B | HOH474 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00895","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00895","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"27422871","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3BGV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E9J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E9W","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27422871","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3BGV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E9J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E9W","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Site: {"description":"mRNA cap binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00895","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
