6J4S
| Structural basis of tubulin detyrosination by vasohibins-SVBP enzyme complex and functional implications | Descriptor: | GLYCEROL, PHOSPHATE ION, Small vasohibin-binding protein, ... | Authors: | Wang, N, Bao, H, Huang, H. | Deposit date: | 2019-01-10 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex. Nat.Struct.Mol.Biol., 26, 2019
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1NYF
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6CC9
| NMR data-driven model of GTPase KRas-GMPPNP:Cmpd2 complex tethered to a nanodisc | Descriptor: | (2R,4S)-4-[(5-bromo-1H-indole-3-carbonyl)amino]-2-[(4-chlorophenyl)methyl]piperidin-1-ium, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, ... | Authors: | Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M. | Deposit date: | 2018-02-06 | Release date: | 2018-09-05 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site. Cell Chem Biol, 25, 2018
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1PRM
| TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS | Descriptor: | C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND PLR1 (AFAPPLPRR) | Authors: | Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L. | Deposit date: | 1994-10-10 | Release date: | 1995-02-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions. Science, 266, 1994
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1PRL
| TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS | Descriptor: | C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND PLR1 (AFAPPLPRR) | Authors: | Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L. | Deposit date: | 1994-10-10 | Release date: | 1995-02-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions. Science, 266, 1994
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6GOD
| KRAS full length wild-type GPPNHP | Descriptor: | GLYCEROL, GTPase KRas, MAGNESIUM ION, ... | Authors: | Cruz-Migoni, A, Quevedo, C.E, Carr, S.B, Ehebauer, M.T, Phillips, S.V.E, Rabbitts, T.H. | Deposit date: | 2018-06-01 | Release date: | 2019-02-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6C4S
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6CDS
| Human neurofibromin 2/merlin/schwannomin residues 1-339 in complex with PIP2 | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Merlin, ... | Authors: | Chinthalapudi, K, Sharff, A.J, Bricogne, G, Izard, T. | Deposit date: | 2018-02-09 | Release date: | 2018-07-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2. Nat Commun, 9, 2018
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6CM9
| Structure of the cargo bound AP-1:Arf1:tetherin-Nef closed trimer monomeric subunit | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. | Deposit date: | 2018-03-03 | Release date: | 2018-08-08 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.73 Å) | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
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1QG7
| STROMA CELL-DERIVED FACTOR-1ALPHA (SDF-1ALPHA) | Descriptor: | STROMAL CELL-DERIVED FACTOR 1 ALPHA, SULFATE ION | Authors: | Senda, T, Nandhagopal, N, Sugimoto, K, Mitsui, Y. | Deposit date: | 1999-04-21 | Release date: | 2001-02-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of recombinant native SDF-1alpha with additional mutagenesis studies: an attempt at a more comprehensive interpretation of accumulated structure-activity relationship data. J.Interferon Cytokine Res., 20, 2000
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6CIT
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6K81
| Crystal structure of human VASH1-SVBP complex | Descriptor: | Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 1 | Authors: | Liu, X, Wang, H, Zhang, Y, Feng, Y. | Deposit date: | 2019-06-11 | Release date: | 2020-02-19 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural insights into tubulin detyrosination by vasohibins-SVBP complex. Cell Discov, 5, 2019
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3DFS
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6BI7
| Crystal structure of Rev7-WT/Rev3 as a monomer under high-salt conditions | Descriptor: | DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B | Authors: | Rizzo, A.A, Korzhnev, D.M, Hao, B, Li, Y. | Deposit date: | 2017-11-01 | Release date: | 2018-08-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1QS2
| CRYSTAL STRUCTURE OF VIP2 WITH NAD | Descriptor: | ADP-RIBOSYLTRANSFERASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Han, S, Craig, J.A, Putnam, C.D, Carozzi, N.B, Tainer, J.A. | Deposit date: | 1999-06-25 | Release date: | 1999-12-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Evolution and mechanism from structures of an ADP-ribosylating toxin and NAD complex. Nat.Struct.Biol., 6, 1999
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6CRI
| Structure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimer | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Morris, K.L, Buffalo, C.Z, Hurley, J.H. | Deposit date: | 2018-03-18 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
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1QS1
| CRYSTAL STRUCTURE OF VEGETATIVE INSECTICIDAL PROTEIN2 (VIP2) | Descriptor: | ADP-RIBOSYLTRANSFERASE | Authors: | Han, S, Craig, J.A, Putnam, C.D, Carozzi, N.B, Tainer, J.A. | Deposit date: | 1999-06-25 | Release date: | 1999-12-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Evolution and mechanism from structures of an ADP-ribosylating toxin and NAD complex. Nat.Struct.Biol., 6, 1999
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7D4I
| Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA helicase Dhr1 (State F) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Du, Y, Zhang, J, An, W, Ye, K. | Deposit date: | 2020-09-24 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structure of 90S small ribosomal precursors complex with Dhr1 To Be Published
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7D63
| Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Du, Y, Zhang, J, An, W, Ye, K. | Deposit date: | 2020-09-29 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (12.3 Å) | Cite: | Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) To Be Published
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3FCU
| Structure of headpiece of integrin aIIBb3 in open conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, CALCIUM ION, ... | Authors: | Zhu, J, Luo, B.-H, Xiao, T, Zhang, C, Nishida, N, Springer, T.A. | Deposit date: | 2008-11-22 | Release date: | 2009-01-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol.Cell, 32, 2008
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6CTC
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6CCX
| NMR data-driven model of GTPase KRas-GMPPNP:Cmpd2 complex tethered to a nanodisc | Descriptor: | (2R,4S)-4-[(5-bromo-1H-indole-3-carbonyl)amino]-2-[(4-chlorophenyl)methyl]piperidin-1-ium, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, ... | Authors: | Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M. | Deposit date: | 2018-02-07 | Release date: | 2018-09-05 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site. Cell Chem Biol, 25, 2018
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6CCH
| NMR data-driven model of GTPase KRas-GMPPNP tethered to a nanodisc (E3 state) | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... | Authors: | Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M. | Deposit date: | 2018-02-07 | Release date: | 2018-08-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site. Cell Chem Biol, 25, 2018
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3DFN
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3DFP
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