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6GOD

KRAS full length wild-type GPPNHP

Summary for 6GOD
Entry DOI10.2210/pdb6god/pdb
DescriptorGTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (5 entities in total)
Functional Keywordskras full lenght, oncoprotein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight20237.99
Authors
Cruz-Migoni, A.,Quevedo, C.E.,Carr, S.B.,Ehebauer, M.T.,Phillips, S.V.E.,Rabbitts, T.H. (deposition date: 2018-06-01, release date: 2019-02-06, Last modification date: 2024-01-17)
Primary citationCruz-Migoni, A.,Canning, P.,Quevedo, C.E.,Bataille, C.J.R.,Bery, N.,Miller, A.,Russell, A.J.,Phillips, S.E.V.,Carr, S.B.,Rabbitts, T.H.
Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Proc. Natl. Acad. Sci. U.S.A., 116:2545-2550, 2019
Cited by
PubMed: 30683716
DOI: 10.1073/pnas.1811360116
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.71 Å)
Structure validation

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