8E7W
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![BU of 8e7w by Molmil](/molmil-images/mine/8e7w) | RsTSPO A139T with Heme | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | Deposit date: | 2022-08-25 | Release date: | 2023-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity. Biochemistry, 62, 2023
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2O0F
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![BU of 2o0f by Molmil](/molmil-images/mine/2o0f) | Docking of the modified RF3 X-ray structure into cryo-EM map of E.coli 70S ribosome bound with RF3 | Descriptor: | Peptide chain release factor 3 | Authors: | Gao, H, Zhou, Z, Rawat, U, Huang, C, Bouakaz, L, Wang, C, Liu, Y, Zavialov, A, Gursky, R, Sanyal, S, Ehrenberg, M, Frank, J, Song, H. | Deposit date: | 2006-11-27 | Release date: | 2007-07-24 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (15.5 Å) | Cite: | RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors Cell(Cambridge,Mass.), 129, 2007
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5JSN
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![BU of 5jsn by Molmil](/molmil-images/mine/5jsn) | Bcl2-inhibitor complex | Descriptor: | Apoptosis regulator Bcl-2, Bcl2 inhibitor | Authors: | Shen, B.W, Stoddard, B.L. | Deposit date: | 2016-05-09 | Release date: | 2016-11-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer. Elife, 5, 2016
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2NXJ
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2NTS
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![BU of 2nts by Molmil](/molmil-images/mine/2nts) | Crystal Structure of SEK-hVb5.1 | Descriptor: | Staphylococcal enterotoxin K, TRBC1 protein | Authors: | Gunther, S, Varma, A.K, Moza, B, Sundberg, E.J. | Deposit date: | 2006-11-08 | Release date: | 2007-06-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A novel loop domain in superantigens extends their T cell receptor recognition site J.Mol.Biol., 371, 2007
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2NXF
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![BU of 2nxf by Molmil](/molmil-images/mine/2nxf) | Crystal Structure of a dimetal phosphatase from Danio rerio LOC 393393 | Descriptor: | ETHANOL, PHOSPHATE ION, Putative dimetal phosphatase, ... | Authors: | Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, McCoy, J.G, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2006-11-17 | Release date: | 2006-12-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of a dimetal phosphatase from Danio rerio LOC 393393 To be Published
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2O2F
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![BU of 2o2f by Molmil](/molmil-images/mine/2o2f) | Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand | Descriptor: | 4-(4-BENZYL-4-METHOXYPIPERIDIN-1-YL)-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE, Apoptosis regulator Bcl-2 | Authors: | Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. | Deposit date: | 2006-11-29 | Release date: | 2007-02-27 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
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2O57
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![BU of 2o57 by Molmil](/molmil-images/mine/2o57) | Crystal Structure of a putative sarcosine dimethylglycine methyltransferase from Galdieria sulphuraria | Descriptor: | putative sarcosine dimethylglycine methyltransferase | Authors: | Mccoy, J.G, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2006-12-05 | Release date: | 2006-12-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.946 Å) | Cite: | Crystal Structure of a putative sarcosine dimethylglycine methyltransferase from Galdieria sulphuraria To be Published
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2PE5
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![BU of 2pe5 by Molmil](/molmil-images/mine/2pe5) | Crystal Structure of the Lac Repressor bound to ONPG in repressed state | Descriptor: | 2-nitrophenyl beta-D-galactopyranoside, DNA (5'-D(*DAP*DAP*DTP*DTP*DGP*DTP*DGP*DAP*DGP*DCP*DGP*DCP*DTP*DCP*DAP*DCP*DAP*DAP*DTP*DT)-3'), Lactose operon repressor | Authors: | Daber, R, Stayrook, S.E, Rosenberg, A, Lewis, M. | Deposit date: | 2007-04-02 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural analysis of lac repressor bound to allosteric effectors J.Mol.Biol., 370, 2007
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3MTG
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![BU of 3mtg by Molmil](/molmil-images/mine/3mtg) | Crystal structure of human S-adenosyl homocysteine hydrolase-like 1 protein | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative adenosylhomocysteinase 2 | Authors: | Wisniewska, M, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schutz, P, Thorsell, A.G, Tresaugues, L, van der Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-04-30 | Release date: | 2010-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Crystal structure of human S-adenosyl homocysteine hydrolase-like 1 protein TO BE PUBLISHED
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2OUT
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![BU of 2out by Molmil](/molmil-images/mine/2out) | Solution Structure of HI1506, a Novel Two Domain Protein from Haemophilus influenzae | Descriptor: | Mu-like prophage FluMu protein gp35, Protein HI1507 in Mu-like prophage FluMu region | Authors: | Sari, N, He, Y, Doseeva, V, Surabian, K, Schwarz, F, Herzberg, O, Orban, J, Structure 2 Function Project (S2F) | Deposit date: | 2007-02-12 | Release date: | 2007-05-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of HI1506, a novel two-domain protein from Haemophilus influenzae. Protein Sci., 16, 2007
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6GG8
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![BU of 6gg8 by Molmil](/molmil-images/mine/6gg8) | Mineralocorticoid receptor in complex with (s)-13 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Mineralocorticoid receptor, Nuclear receptor coactivator 1, ... | Authors: | Edman, K, Aagaard, A, Tangefjord, S. | Deposit date: | 2018-05-03 | Release date: | 2019-01-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Identification of Mineralocorticoid Receptor Modulators with Low Impact on Electrolyte Homeostasis but Maintained Organ Protection. J.Med.Chem., 62, 2019
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2P5M
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![BU of 2p5m by Molmil](/molmil-images/mine/2p5m) | C-terminal domain hexamer of AhrC bound with L-arginine | Descriptor: | ARGININE, Arginine repressor | Authors: | Garnett, J.A, Baumberg, S, Stockley, P.G, Phillips, S.E.V. | Deposit date: | 2007-03-15 | Release date: | 2007-10-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of the C-terminal effector-binding domain of AhrC bound to its corepressor L-arginine. Acta Crystallogr.,Sect.F, 63, 2007
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2ODJ
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2NTT
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![BU of 2ntt by Molmil](/molmil-images/mine/2ntt) | Crystal Structure of SEK | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Staphylococcal enterotoxin K | Authors: | Gunther, S, Varma, A.K, Moza, B, Sundberg, E.J. | Deposit date: | 2006-11-08 | Release date: | 2007-06-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.561 Å) | Cite: | A novel loop domain in superantigens extends their T cell receptor recognition site J.Mol.Biol., 371, 2007
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2NVZ
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![BU of 2nvz by Molmil](/molmil-images/mine/2nvz) | RNA Polymerase II elongation complex with UTP, updated 11/2006 | Descriptor: | 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... | Authors: | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | Deposit date: | 2006-11-14 | Release date: | 2006-12-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis Cell(Cambridge,Mass.), 127, 2006
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2O55
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![BU of 2o55 by Molmil](/molmil-images/mine/2o55) | Crystal Structure of a putative glycerophosphodiester phosphodiesterase from Galdieria sulphuraria | Descriptor: | SULFATE ION, putative glycerophosphodiester phosphodiesterase | Authors: | Mccoy, J.G, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2006-12-05 | Release date: | 2006-12-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.806 Å) | Cite: | Crystal Structure of a putative glycerophosphodiester phosphodiesterase from Galdieria sulphuraria To be Published
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2O6V
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2NUP
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2O21
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![BU of 2o21 by Molmil](/molmil-images/mine/2o21) | Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand | Descriptor: | 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-2 | Authors: | Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. | Deposit date: | 2006-11-29 | Release date: | 2007-02-27 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
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2NXN
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![BU of 2nxn by Molmil](/molmil-images/mine/2nxn) | T. thermophilus ribosomal protein L11 methyltransferase (PrmA) in complex with ribosomal protein L11 | Descriptor: | 50S ribosomal protein L11, Ribosomal protein L11 methyltransferase | Authors: | Demirci, H, Gregory, S.T, Dahlberg, A.E, Jogl, G. | Deposit date: | 2006-11-17 | Release date: | 2006-12-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA. Embo J., 26, 2007
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8HFQ
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![BU of 8hfq by Molmil](/molmil-images/mine/8hfq) | Cryo-EM structure of CpcL-PBS from cyanobacterium Synechocystis sp. PCC 6803 | Descriptor: | C-phycocyanin alpha subunit, C-phycocyanin beta subunit, Ferredoxin--NADP reductase, ... | Authors: | Zheng, L, Zhang, Z, Wang, H, Zheng, Z, Gao, N, Zhao, J. | Deposit date: | 2022-11-11 | Release date: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | Cryo-EM and femtosecond spectroscopic studies provide mechanistic insight into the energy transfer in CpcL-phycobilisomes. Nat Commun, 14, 2023
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2OCV
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![BU of 2ocv by Molmil](/molmil-images/mine/2ocv) | Structural basis of Na+ activation mimicry in murine thrombin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombin | Authors: | Marino, F, Chen, Z, Ergenekan, C.E, Bush, L.A, Mathews, F.S, Di Cera, E. | Deposit date: | 2006-12-21 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of na+ activation mimicry in murine thrombin. J.Biol.Chem., 282, 2007
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7NUG
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7NUH
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![BU of 7nuh by Molmil](/molmil-images/mine/7nuh) | |