8E7W

RsTSPO A139T with Heme

Summary for 8E7W

• Entry DOI: 10.2210/pdb8e7w/pdb
• Related: 4UC1
• Descriptor: Tryptophan-rich sensory protein, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, ... (5 entities in total)
• Functional Keywords: translocator protein 18 kd, tspo, membrane protein
• Biological source: Cereibacter sphaeroides
• Total number of polymer chains: 3
• Total formula weight: 61113.32

Authors

Liu, J.,Hiser, C.,Li, F.,Garavito, R.,Ferguson-Miller, S. (deposition date: 2022-08-25, release date: 2023-03-29, Last modification date: 2023-10-25)

• Primary citation: Liu, J.,Hiser, C.,Li, F.,Hall, R.,Garavito, R.M.,Ferguson-Miller, S.; New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity.; Biochemistry, 62:1262-1273, 2023; PubMed: 36947867; DOI: 10.1021/acs.biochem.2c00612

Experimental method

X-RAY DIFFRACTION (2.1 Å)