PDB: 289 resultsInfo pagesStatus searchChemie searchBIRD

---

4RNO	Crystal structure of human polymerase eta extending an abasic site-dA pair by inserting dCTP opposite template G Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase eta, ... Authors: Patra, A, Egli, M. Deposit date: 2014-10-24 Release date: 2015-02-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.82 Å) Cite: Structural and Kinetic Analysis of Nucleoside Triphosphate Incorporation Opposite an Abasic Site by Human Translesion DNA Polymerase eta. J.Biol.Chem., 290, 2015
4O3O	Crystal structure of human polymerase eta inserting datp opposite an 8-oxog containing dna template Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(8OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Patra, A, Egli, M. Deposit date: 2013-12-18 Release date: 2014-04-30 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.698 Å) Cite: Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
4O3S	Crystal structure of human polymerase eta extending an 8-oxog dna lesion: post insertion of 8-oxog-dc pair Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*C)-3'), DNA (5'-D(*CP*AP*TP*GP*(8OG)P*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Patra, A, Egli, M. Deposit date: 2013-12-18 Release date: 2014-04-30 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.717 Å) Cite: Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
4RNM	Crystal structure of human polymerase eta inserting dAMPnPP opposite DNA template containing an abasic site Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA Primar: AGCGTCAT, DNA Template: CAT(3DR)ATGACGCT, ... Authors: Patra, A, Egli, M. Deposit date: 2014-10-24 Release date: 2015-02-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.144 Å) Cite: Structural and Kinetic Analysis of Nucleoside Triphosphate Incorporation Opposite an Abasic Site by Human Translesion DNA Polymerase eta. J.Biol.Chem., 290, 2015
2R8J	Structure of the Eukaryotic DNA Polymerase eta in complex with 1,2-d(GpG)-cisplatin containing DNA Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, Cisplatin, ... Authors: Carell, T, Alt, A, Lammens, K. Deposit date: 2007-09-11 Release date: 2007-12-11 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase eta Science, 318, 2007
2R8K	Structure of the Eukaryotic DNA Polymerase eta in complex with 1,2-d(GpG)-cisplatin containing DNA Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*DGP*DTP*DGP*DGP*DTP*DGP*DAP*DGP*DC)-3', 5'-D(P*DGP*DGP*DCP*DTP*DCP*DAP*DCP*DCP*DAP*DC)-3', ... Authors: Carell, T, Alt, A, Lammens, K. Deposit date: 2007-09-11 Release date: 2007-12-11 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase eta Science, 318, 2007
2LSK	C-terminal domain of human REV1 in complex with DNA-polymerase H (eta) Descriptor: DNA polymerase eta, DNA repair protein REV1 Authors: Pozhidaeva, A, Pustovalova, Y, Bezsonova, I, Korzhnev, D. Deposit date: 2012-05-01 Release date: 2012-06-27 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase eta. Biochemistry, 51, 2012
8FOG	Crystal structure of human DNA polymerase eta incorporating dITP across dT Descriptor: 2'-deoxyinosine 5'-triphosphate, CALCIUM ION, DNA polymerase eta, ... Authors: Jung, H. Deposit date: 2022-12-30 Release date: 2023-05-03 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Crystal structure of human DNA polymerase eta incorporating dITP across dT To Be Published
8FN3	Crystal structure of human DNA polymerase eta incorporating dITP across dC Descriptor: 2'-deoxyinosine 5'-triphosphate, CALCIUM ION, DNA polymerase eta, ... Authors: Jung, H. Deposit date: 2022-12-26 Release date: 2023-05-03 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.17 Å) Cite: Crystal structure of human DNA polymerase eta incorporating dITP across dC To Be Published
8G8H	Crystal structure of human DNA polymerase eta incorporating ITP across dC Descriptor: CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*GP*AP*G)-3'), DNA (5'-D(P*AP*TP*CP*CP*TP*CP*AP*CP*GP*CP*T)-3'), ... Authors: Jung, H. Deposit date: 2023-02-17 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Crystal structure of human DNA polymerase eta incorporating ITP across dC To Be Published
8GML	Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dG Descriptor: 2'-deoxy-5-fluorouridine 5'-(tetrahydrogen triphosphate), CALCIUM ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), ... Authors: Jung, H. Deposit date: 2023-03-26 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (2.567 Å) Cite: Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA To Be Published
8GKR	Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA Descriptor: 2'-deoxy-5-fluorouridine 5'-(tetrahydrogen triphosphate), CALCIUM ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), ... Authors: Jung, H. Deposit date: 2023-03-20 Release date: 2023-09-20 Method: X-RAY DIFFRACTION (2.784 Å) Cite: Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA To Be Published
8G8J	Crystal structure of human DNA polymerase eta incorporating ITP across dT Descriptor: CALCIUM ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), DNA (5'-D(P*AP*TP*TP*CP*TP*CP*AP*CP*AP*CP*T)-3'), ... Authors: Jung, H. Deposit date: 2023-02-17 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Crystal structure of human DNA polymerase eta incorporating ITP across dT To Be Published
8GBF	Crystal structure of human DNA polymerase eta incorporating syn-ITP across dT Descriptor: CALCIUM ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), DNA (5'-D(P*AP*TP*TP*CP*TP*CP*AP*CP*AP*CP*T)-3'), ... Authors: Jung, H. Deposit date: 2023-02-25 Release date: 2024-02-28 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Crystal structure of human DNA polymerase eta incorporating syn-ITP across dT To Be Published
4YQW	Mutant Human DNA Polymerase Eta Q38A/R61A Inserting dCTP Opposite Template G Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Su, Y, Patra, A, Harp, J.M, Egli, M, Guengerich, F.P. Deposit date: 2015-03-13 Release date: 2015-05-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.064 Å) Cite: Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase eta in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2'-deoxyguanosine. J.Biol.Chem., 290, 2015
4YR3	Mutant Human DNA Polymerase Eta R61M Inserting dCTP Opposite Template G Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Su, Y, Patra, A, Harp, J.M, Egli, M, Guengerich, F.P. Deposit date: 2015-03-14 Release date: 2015-05-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase eta in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2'-deoxyguanosine. J.Biol.Chem., 290, 2015
4YP3	Mutant Human DNA Polymerase Eta Q38A/R61A Inserting dCTP Opposite an 8-Oxoguanine Lesion Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Su, Y, Patra, A, Harp, J.M, Egli, M, Guengerich, F.P. Deposit date: 2015-03-12 Release date: 2015-05-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase eta in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2'-deoxyguanosine. J.Biol.Chem., 290, 2015
4YR0	Mutant Human DNA Polymerase Eta R61M Inserting dCTP Opposite an 8-Oxoguanine Lesion Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Su, Y, Patra, A, Harp, J.M, Egli, M, Guengerich, F.P. Deposit date: 2015-03-13 Release date: 2015-05-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase eta in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2'-deoxyguanosine. J.Biol.Chem., 290, 2015
4YR2	Mutant Human DNA Polymerase Eta R61M Inserting dATP Opposite an 8-Oxoguanine Lesion Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Su, Y, Patra, A, Harp, J.M, Egli, M, Guengerich, F.P. Deposit date: 2015-03-14 Release date: 2015-05-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase eta in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2'-deoxyguanosine. J.Biol.Chem., 290, 2015
4J9K	Human DNA polymerase eta-DNA ternary complex: misincorporation G opposite T after a T at the primer 3' end (TA/G) Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA, DNA polymerase eta, ... Authors: Zhao, Y, Gregory, M, Biertumpfel, C, Hua, Y, Hanaoka, F, Yang, W. Deposit date: 2013-02-16 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.03 Å) Cite: Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta. Proc.Natl.Acad.Sci.USA, 110, 2013
4J9M	Human DNA polymerase eta-DNA ternary complex: misincorporation G opposite T after an A at the primer 3' end (AA/G) Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA, DNA polymerase eta, ... Authors: Zhao, Y, Gregory, M, Biertumpfel, C, Hua, Y, Hanaoka, F, Yang, W. Deposit date: 2013-02-16 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta. Proc.Natl.Acad.Sci.USA, 110, 2013
4J9N	Human DNA polymerase eta-DNA ternary complex: misincorporation G opposite T after a G at the primer 3' end (GA/G) Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA, DNA polymerase eta, ... Authors: Zhao, Y, Gregory, M, Biertumpfel, C, Hua, Y, Hanaoka, F, Yang, W. Deposit date: 2013-02-16 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.956 Å) Cite: Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta. Proc.Natl.Acad.Sci.USA, 110, 2013
4J9P	Human DNA polymerase eta-DNA postinsertion binary complex with TA base pair Descriptor: DNA (5'-D(*C*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), DNA polymerase eta, ... Authors: Zhao, Y, Gregory, M, Biertumpfel, C, Hua, Y, Hanaoka, F, Yang, W. Deposit date: 2013-02-16 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta. Proc.Natl.Acad.Sci.USA, 110, 2013
4J9L	Human DNA polymerase eta-DNA ternary complex: misincorporation G opposite T after a C at the primer 3' end (CA/G) Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA, DNA polymerase eta, ... Authors: Zhao, Y, Gregory, M, Biertumpfel, C, Hua, Y, Hanaoka, F, Yang, W. Deposit date: 2013-02-16 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta. Proc.Natl.Acad.Sci.USA, 110, 2013
4J9R	Human DNA polymerase eta-DNA translocated binary complex with TG mispair Descriptor: DNA (5'-D(*T*AP*CP*TP*TP*AP*TP*GP*AP*CP*GP*T)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*CP*AP*TP*G)-3'), DNA polymerase eta, ... Authors: Zhao, Y, Gregory, M, Biertumpfel, C, Hua, Y, Hanaoka, F, Yang, W. Deposit date: 2013-02-16 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta. Proc.Natl.Acad.Sci.USA, 110, 2013

<123456789101112>