4RNO
Crystal structure of human polymerase eta extending an abasic site-dA pair by inserting dCTP opposite template G
Summary for 4RNO
Entry DOI | 10.2210/pdb4rno/pdb |
Related | 4RNM 4RNN |
Descriptor | DNA polymerase eta, Nucleic acids Template: CATG(3DR)TGACGCT, Nucleic acids Primar: AGCGTCAA, ... (7 entities in total) |
Functional Keywords | protein, dna, dna damage dna-directed dna polymerase, adenosine triphosphate, y-family polymerase, trans-lesion synthesis (tls), dna binding, abasic site lesion bypass, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : Q9Y253 |
Total number of polymer chains | 3 |
Total formula weight | 55181.96 |
Authors | |
Primary citation | Patra, A.,Zhang, Q.,Lei, L.,Su, Y.,Egli, M.,Guengerich, F.P. Structural and Kinetic Analysis of Nucleoside Triphosphate Incorporation Opposite an Abasic Site by Human Translesion DNA Polymerase eta. J.Biol.Chem., 290:8028-8038, 2015 Cited by PubMed: 25666608DOI: 10.1074/jbc.M115.637561 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.82 Å) |
Structure validation
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