4RNO
Crystal structure of human polymerase eta extending an abasic site-dA pair by inserting dCTP opposite template G
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase eta | polymer | 435 | 48617.7 | 1 | UniProt (Q9Y253) Pfam (PF00817) Pfam (PF21704) Pfam (PF11799) | Homo sapiens (human) | RAD30 homolog A, Xeroderma pigmentosum variant type protein |
| 2 | B (T) | Nucleic acids Template: CATG(3DR)TGACGCT | polymer | 12 | 3529.3 | 1 | synthetic construct | ||
| 3 | C (P) | Nucleic acids Primar: AGCGTCAA | polymer | 8 | 2435.6 | 1 | synthetic construct | ||
| 4 | D (A) | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE | non-polymer | 467.2 | 1 | Chemie (DCP) | |||
| 5 | E (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | G, H, I (A, T, P) | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 54582.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 599.3 | |
| All* | Total formula weight | 55182.0 |
