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4RNO

Crystal structure of human polymerase eta extending an abasic site-dA pair by inserting dCTP opposite template G

Functional Information from GO Data
ChainGOidnamespacecontents
A0003684molecular_functiondamaged DNA binding
A0006281biological_processDNA repair
Functional Information from PDB Data
site_idAC1
Number of Residues15
DetailsBINDING SITE FOR RESIDUE DCP A 501
ChainResidue
AASP13
AASP115
ALYS231
ACA502
AHOH629
PDA8
TDG4
AMET14
ACYS16
APHE17
APHE18
AILE48
ATYR52
AARG55
AARG61

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CA A 502
ChainResidue
AASP13
AMET14
AASP115
ADCP501

site_idAC3
Number of Residues1
DetailsBINDING SITE FOR RESIDUE GOL A 503
ChainResidue
AHOH642

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO
ChainResidueDetails
AASP13
AMET14
AASP115
AGLU116

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:27284197
ChainResidueDetails
AARG61

227111

PDB entries from 2024-11-06

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