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4J9K

Human DNA polymerase eta-DNA ternary complex: misincorporation G opposite T after a T at the primer 3' end (TA/G)

Summary for 4J9K
Entry DOI10.2210/pdb4j9k/pdb
Related3MR2 4DL2 4DL3 4J9L 4J9M 4J9N 4J9O 4J9P 4J9Q 4J9R 4J9S
DescriptorDNA polymerase eta, DNA, MAGNESIUM ION, ... (7 entities in total)
Functional Keywordsimmunoglobulin, a to g transition, misincorporation, wobble base pair, dna polymerase, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus: Q9Y253
Total number of polymer chains3
Total formula weight56903.67
Authors
Zhao, Y.,Gregory, M.,Biertumpfel, C.,Hua, Y.,Hanaoka, F.,Yang, W. (deposition date: 2013-02-16, release date: 2013-05-01, Last modification date: 2023-09-20)
Primary citationZhao, Y.,Gregory, M.T.,Biertumpfel, C.,Hua, Y.J.,Hanaoka, F.,Yang, W.
Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110:8146-8151, 2013
Cited by
PubMed: 23630267
DOI: 10.1073/pnas.1303126110
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.03 Å)
Structure validation

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