4J9K

Human DNA polymerase eta-DNA ternary complex: misincorporation G opposite T after a T at the primer 3' end (TA/G)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 501

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	MG502
A	XG4503

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG A 502

Chain	Residue
A	XG4503
A	HOH744
A	HOH828
P	DT9
A	ASP13
A	ASP115
A	GLU116
A	MG501

---

site_id	AC3
Number of Residues	28
Details	BINDING SITE FOR RESIDUE XG4 A 503

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	PHE18
A	GLN38
A	ILE48
A	ALA49
A	TYR52
A	ARG55
A	ARG61
A	ASP115
A	LYS231
A	MG501
A	MG502
A	HOH614
A	HOH641
A	HOH643
A	HOH699
A	HOH713
A	HOH734
A	HOH744
A	HOH788
A	HOH828
P	DT9
T	DT5
T	DA6

---

site_id	AC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL A 504

Chain	Residue
A	ARG24
A	GLN25
A	PRO244
A	PHE247
A	SER248
A	GLY276
A	GLU277
A	HOH630
A	HOH656
A	HOH752
A	HOH776

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 505

Chain	Residue
A	GLU148
A	GLY149
A	LEU150
A	MET166
A	THR388
A	ARG389
A	HOH657
A	HOH675

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE XG4 A 506

Chain	Residue
A	SER257
A	LYS293
A	ASN294
A	TRP297

---

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL T 101

Chain	Residue
A	THR318
A	PHE423
A	CYS425
T	DG8
T	DA9
T	DC10
T	HOH207

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL P 101

Chain	Residue
A	CYS384
P	DG3
P	DC4

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL P 102

Chain	Residue
P	DC7
P	DA8
T	DG8
T	DA9
T	DC10

---

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL P 103

Chain	Residue
A	PHE325
A	THR329
A	LEU331
A	GLN336
A	TRP340
P	DG3
P	DC4
T	DT13

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KFO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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