8GKR

Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA

Summary for 8GKR

• Entry DOI: 10.2210/pdb8gkr/pdb
• Descriptor: DNA polymerase eta, DNA (5'-D(P*AP*TP*AP*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), ... (7 entities in total)
• Functional Keywords: dna damage, dna replication, translesion synthesis, transferase-dna complex, anti-cancer, 5-fu, transferase/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 55425.17

Authors

Jung, H. (deposition date: 2023-03-20, release date: 2023-09-20)

• Primary citation: Jung, H.; Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.784 Å)