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8GKR

Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA polymerase etapolymer43248325.41UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
In PDB
Homo sapiens (human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2TDNA (5'-D(P*AP*TP*AP*CP*TP*CP*AP*CP*AP*CP*T)-3')polymer123566.41Homo sapiens
3PDNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3')polymer82506.71Homo sapiens
4A2'-deoxy-5-fluorouridine 5'-(tetrahydrogen triphosphate)non-polymer486.11Chemie (B7P)
5AGLYCEROLnon-polymer92.15Chemie (GOL)
6ACALCIUM IONnon-polymer40.12Chemie (CA)
7waterwater18.05Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54398.4
Non-Polymers*Number of molecules8
Total formula weight1026.8
All*Total formula weight55425.2
*Water molecules are not included.

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PDB entries from 2024-07-31

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