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8GKR

Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer43248325.41UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
Homo sapiens (human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2B
(T)
DNA (5'-D(P*AP*TP*AP*CP*TP*CP*AP*CP*AP*CP*T)-3')polymer123566.41Homo sapiens
3C
(P)
DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3')polymer82506.71Homo sapiens
4D
(A)
2'-deoxy-5-fluorouridine 5'-(tetrahydrogen triphosphate)non-polymer486.11Chemie (B7P)
5E, F, G, H, I
(A)
GLYCEROLnon-polymer92.15Chemie (GOL)
6J, K
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
7L, M
(A, P)
waterwater18.05Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54398.4
Non-Polymers*Number of molecules8
Total formula weight1026.8
All*Total formula weight55425.2
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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