8GML

Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dG

Summary for 8GML

• Entry DOI: 10.2210/pdb8gml/pdb
• Descriptor: DNA polymerase eta, DNA (5'-D(P*TP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), ... (6 entities in total)
• Functional Keywords: dna damage, dna replication, translesion synthesis, transferase-dna complex, anti-cancer, 5-fu, transferase/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 54940.62

Authors

Jung, H. (deposition date: 2023-03-26, release date: 2023-09-20)

• Primary citation: Jung, H.; Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.567 Å)