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8GML

Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dG

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA polymerase etapolymer43248325.41UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
In PDB
Homo sapiens (human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2TDNA (5'-D(P*TP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3')polymer123582.41Homo sapiens
3PDNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3')polymer82506.71Homo sapiens
4A2'-deoxy-5-fluorouridine 5'-(tetrahydrogen triphosphate)non-polymer486.11Chemie (B7P)
5ACALCIUM IONnon-polymer40.11Chemie (CA)
6waterwater18.048Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54414.4
Non-Polymers*Number of molecules2
Total formula weight526.2
All*Total formula weight54940.6
*Water molecules are not included.

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PDB entries from 2024-07-31

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