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3MXW
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BU of 3mxw by Molmil
Crystal structure Sonic hedgehog bound to the 5E1 fab fragment
Descriptor: 5E1 heavy chain, 5E1 light chain, CALCIUM ION, ...
Authors:Hymowitz, S.G, Maun, H.R.
Deposit date:2010-05-07
Release date:2010-05-26
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Hedgehog pathway antagonist 5E1 binds hedgehog at the pseudo-active site.
J.Biol.Chem., 285, 2010
3MXX
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BU of 3mxx by Molmil
Crystal structure of WDR5 mutant (S62A)
Descriptor: WD repeat-containing protein 5
Authors:Wu, Y.-D, Wu, X.-H, Gao, Y, Chen, R.-C.
Deposit date:2010-05-08
Release date:2010-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Effect of Asp-His-Ser/Thr-Trp Tetrad on the Thermostability of WD40-Repeat Proteins
Biochemistry, 49, 2010
3MXY
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BU of 3mxy by Molmil
Structures of Grb2-SH2 Domain and AICD peptide Complexes Reveal a Conformational Switch and Their Functional Implications.
Descriptor: AICD peptide E683V variant, Growth factor receptor-bound protein 2
Authors:Sen, U, Das, S.
Deposit date:2010-05-08
Release date:2011-05-11
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain.
J.Mol.Biol., 414, 2011
3MXZ
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BU of 3mxz by Molmil
Crystal Structure of tubulin folding cofactor A from Arabidopsis thaliana
Descriptor: NITRATE ION, Tubulin-specific chaperone A
Authors:Lu, L, Nan, J, Mi, W, Su, X.D, Li, Y.
Deposit date:2010-05-08
Release date:2010-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:Crystal structure of tubulin folding cofactor A from Arabidopsis thaliana and its beta-tubulin binding characterization
Febs Lett., 584, 2010
3MY0
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BU of 3my0 by Molmil
Crystal structure of the ACVRL1 (ALK1) kinase domain bound to LDN-193189
Descriptor: 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline, Serine/threonine-protein kinase receptor R3
Authors:Chaikuad, A, Alfano, I, Cooper, C, Mahajan, P, Daga, N, Sanvitale, C, Fedorov, O, Petrie, K, Savitsky, P, Gileadi, O, Sethi, R, Krojer, T, Muniz, J.R.C, Pike, A.C.W, Vollmar, M, Carpenter, C.P, Ugochukwu, E, Knapp, S, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC)
Deposit date:2010-05-08
Release date:2010-07-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A small molecule targeting ALK1 prevents Notch cooperativity and inhibits functional angiogenesis.
Angiogenesis, 18, 2015
3MY1
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BU of 3my1 by Molmil
Structure of CDK9/cyclinT1 in complex with DRB
Descriptor: 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole, Cell division protein kinase 9, Cyclin-T1, ...
Authors:Baumli, S, Johnson, L.N.
Deposit date:2010-05-09
Release date:2010-09-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Halogen bonds form the basis for selective P-TEFb inhibition by DRB
Chem.Biol., 17, 2010
3MY2
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BU of 3my2 by Molmil
Crystal structure of LptC
Descriptor: Lipopolysaccharide export system protein lptC
Authors:Tran, A.X, Dong, C, Whitfield, C, Scottish Structural Proteomics Facility (SSPF)
Deposit date:2010-05-09
Release date:2010-09-01
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and functional analysis of LptC, a conserved membrane protein involved in the lipopolysaccharide export pathway in Escherichia coli.
J.Biol.Chem., 285, 2010
3MY5
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BU of 3my5 by Molmil
CDk2/cyclinA in complex with DRB
Descriptor: 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole, Cell division protein kinase 2, Cyclin-A2, ...
Authors:Baumli, S, Johnson, L.N.
Deposit date:2010-05-09
Release date:2010-09-29
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Halogen bonds form the basis for selective P-TEFb inhibition by DRB
Chem.Biol., 17, 2010
3MY6
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BU of 3my6 by Molmil
Crystal Structure of the complex of type 1 ribosome inactivating protein with 7-methylguanine at 2.65 A resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-7-methyl-1,7-dihydro-6H-purin-6-one, Ribosome-inactivating protein momordin I
Authors:Kushwaha, G.S, Singh, N, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2010-05-10
Release date:2010-08-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structure of the complex of type 1 ribosome inactivating protein with 7-methylguanine at 2.65 A resolution
To be Published
3MY7
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BU of 3my7 by Molmil
The Crystal Structure of the ACDH domain of an Alcohol Dehydrogenase from Vibrio parahaemolyticus to 2.25A
Descriptor: Alcohol dehydrogenase/acetaldehyde dehydrogenase, CHLORIDE ION
Authors:Stein, A.J, Weger, A, Volkart, L, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-05-10
Release date:2010-06-02
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Crystal Structure of the ACDH domain of an Alcohol Dehydrogenase from Vibrio parahaemolyticus to 2.25A
To be Published
3MY9
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BU of 3my9 by Molmil
Crystal structure of a muconate cycloisomerase from Azorhizobium caulinodans
Descriptor: GLYCEROL, MAGNESIUM ION, Muconate cycloisomerase
Authors:Quartararo, C.E, Ramagopal, U, Bonanno, J.B, Rutter, M, Bain, K.T, Miller, S, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2010-05-10
Release date:2010-07-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a muconate cycloisomerase from Azorhizobium caulinodans
To be Published
3MYA
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BU of 3mya by Molmil
Crystal Structure of HP67 H41F - P61
Descriptor: Villin-1
Authors:Brown, J.W, Farelli, J.D, McKnight, C.J.
Deposit date:2010-05-10
Release date:2011-06-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:On unsatisfied hydrogen bonds in the N-terminal subdomain of villin headpiece.
J.Mol.Biol., 413, 2011
3MYB
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BU of 3myb by Molmil
Crystal structure of enoyl-coa hydratase mycobacterium smegmatis
Descriptor: Enoyl-CoA hydratase, GLYCEROL
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-05-10
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3MYC
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BU of 3myc by Molmil
Crystal Structure of HP67 H41F - P212121
Descriptor: Villin-1
Authors:Brown, J.W, Farelli, J.D, McKnight, C.J.
Deposit date:2010-05-10
Release date:2011-05-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:On unsatisfied hydrogen bonds in the N-terminal subdomain of villin headpiece.
J.Mol.Biol., 413, 2011
3MYD
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BU of 3myd by Molmil
Structure of the Cytoplasmic domain of FlhA from Helicobacter pylori
Descriptor: Flagellar biosynthesis protein flhA
Authors:Moore, S.A, Jia, Y.
Deposit date:2010-05-10
Release date:2010-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the cytoplasmic domain of the flagellar secretion apparatus component FlhA from Helicobacter pylori.
J.Biol.Chem., 285, 2010
3MYE
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BU of 3mye by Molmil
Crystal Structure of HP67 L61GL
Descriptor: Villin-1
Authors:Brown, J.W, Farelli, J.D, McKnight, C.J.
Deposit date:2010-05-10
Release date:2011-05-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Conserving the Hydrophobic Core at the Expense of Backbone Conformation in Villin Headpiece
To be Published
3MYF
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BU of 3myf by Molmil
The Crystal Structure of the HPT domain from the Hpt Sensor Hybrid Histidine Kinase from Shewanella to 1.80A
Descriptor: Sensor protein
Authors:Stein, A.J, Tesar, C, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-05-10
Release date:2010-05-26
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of the HPT domain from the Hpt Sensor Hybrid Histidine Kinase from Shewanella to 1.80A
To be Published
3MYG
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BU of 3myg by Molmil
Aurora A Kinase complexed with SCH 1473759
Descriptor: 2-{ethyl[(5-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol, Serine/threonine-protein kinase 6, TETRAETHYLENE GLYCOL
Authors:Hruza, A, Prosis, W, Ramanathan, L.
Deposit date:2010-05-10
Release date:2010-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core.
ACS Med Chem Lett, 1, 2010
3MYH
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BU of 3myh by Molmil
Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236
Descriptor: (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Frye, J.J, Klenchin, V.A, Bagshaw, C.R, Rayment, I.
Deposit date:2010-05-10
Release date:2010-05-26
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236
Biochemistry, 49, 2010
3MYI
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BU of 3myi by Molmil
Human metavinculin tail domain
Descriptor: Vinculin
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2010-05-10
Release date:2010-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A helix replacement mechanism directs metavinculin functions.
Plos One, 5, 2010
3MYJ
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BU of 3myj by Molmil
Human Class I MHC HLA-A2 in complex with the WT-1 (126-134) (R1Y) peptide variant.
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-05-10
Release date:2010-08-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A*0201: Implications for WT1-based cancer therapeutics.
Mol.Immunol., 47, 2010
3MYK
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BU of 3myk by Molmil
Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236
Descriptor: (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, MAGNESIUM ION, Myosin-2 heavy chain, ...
Authors:Frye, J.J, Klenchin, V.A, Bagshaw, C.R, Rayment, I.
Deposit date:2010-05-10
Release date:2010-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236
Biochemistry, 49, 2010
3MYL
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BU of 3myl by Molmil
Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236
Descriptor: MAGNESIUM ION, Myosin-2 heavy chain, PYROPHOSPHATE 2-
Authors:Frye, J.J, Klenchin, V.A, Bagshaw, C.R, Rayment, I.
Deposit date:2010-05-10
Release date:2010-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236
Biochemistry, 49, 2010
3MYM
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BU of 3mym by Molmil
Mutation of Methionine-86 in Dehaloperoxidase-hemoglobin: Effects of the Asp-His-Fe Triad in a 3/3 Globin
Descriptor: CYANIDE ION, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:de Serrano, V.S, D'Antonio, E.L, Franzen, S, Bowden, E.F.
Deposit date:2010-05-10
Release date:2011-04-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Functional consequences of the creation of an Asp-His-Fe triad in a 3/3 globin.
Biochemistry, 50, 2011
3MYN
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BU of 3myn by Molmil
Mutation of Methionine-86 in Dehaloperoxidase-hemoglobin: Effects of the Asp-His-Fe Triad in a 3/3 Globin
Descriptor: CYANIDE ION, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Bowden, E.F, de Serrano, V.S, D'Antonio, E.L, Franzen, S.
Deposit date:2010-05-10
Release date:2011-04-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.194 Å)
Cite:Functional consequences of the creation of an Asp-His-Fe triad in a 3/3 globin.
Biochemistry, 50, 2011

236060

数据于2025-05-14公开中

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