3MYA

Crystal Structure of HP67 H41F - P61

Summary for 3MYA

Entry DOI	10.2210/pdb3mya/pdb
Related	1yu5 1yu7 2k6m 2k6n 2rjw 2rjy 3myc 3mye
Descriptor	Villin-1 (2 entities in total)
Functional Keywords	villin headpiece, alpha helix, protein, structural protein
Biological source	Gallus gallus (chicken)
Cellular location	Cytoplasm, cytoskeleton: P02640
Total number of polymer chains	2
Total formula weight	15241.38
Authors	Brown, J.W.,Farelli, J.D.,McKnight, C.J. (deposition date: 2010-05-10, release date: 2011-06-29, Last modification date: 2023-09-06)
Primary citation	Brown, J.W.,Farelli, J.D.,McKnight, C.J. On unsatisfied hydrogen bonds in the N-terminal subdomain of villin headpiece. J.Mol.Biol., 413:543-547, 2011 Cited by PubMed Abstract: Villin headpiece is a small autonomously folding protein that has emerged as a model system for understanding the fundamental tenets governing protein folding. In this communication, we employ NMR and X-ray crystallography to characterize a point mutant, H41F, which retains actin-binding activity, is more thermostable but, interestingly, does not exhibit the partially folded intermediate observed of either wild-type or other similar point mutants. PubMed: 21903098 DOI: 10.1016/j.jmb.2011.08.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation