3MY5

CDk2/cyclinA in complex with DRB

Summary for 3MY5

Related3MY1
DescriptorCell division protein kinase 2, Cyclin-A2, 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole, ... (6 entities in total)
Functional Keywordscdk, cyclin, inhibitor, drb, transferase-protein binding-inhibitor complex, transferase/protein binding/inhibitor
Biological sourceHomo sapiens (human)
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Cellular locationNucleus P30274
Total number of polymer chains4
Total molecular weight129431.14
Authors
Baumli, S.,Johnson, L.N. (deposition date: 2010-05-09, release date: 2010-09-29, Last modification date: 2011-07-13)
Primary citation
Baumli, S.,Endicott, J.A.,Johnson, L.N.
Halogen bonds form the basis for selective P-TEFb inhibition by DRB
Chem.Biol., 17:931-936, 2010
PubMed: 20851342 (PDB entries with the same primary citation)
DOI: 10.1016/j.chembiol.2010.07.012
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21160.4%1.3%6.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report