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3L95
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BU of 3l95 by Molmil
Crystal structure of the human Notch1 Negative Regulatory Region (NRR) bound to the fab fragment of an antagonist antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurogenic locus notch homolog protein 1, ...
Authors:Hymowitz, S.G, de Leon, G.P.
Deposit date:2010-01-04
Release date:2010-03-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Therapeutic antibody targeting of individual Notch receptors.
Nature, 464, 2010
3PSC
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BU of 3psc by Molmil
Bovine GRK2 in complex with Gbetagamma subunits
Descriptor: Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Authors:Thal, D.M, Tesmer, J.J.
Deposit date:2010-12-01
Release date:2011-06-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors.
Mol.Pharmacol., 80, 2011
4BUJ
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BU of 4buj by Molmil
Crystal structure of the S. cerevisiae Ski2-3-8 complex
Descriptor: ANTIVIRAL HELICASE SKI2, ANTIVIRAL PROTEIN SKI8, SULFATE ION, ...
Authors:Halbach, F, Reichelt, P, Rode, M, Conti, E.
Deposit date:2013-06-20
Release date:2013-08-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:The Yeast Ski Complex: Crystal Structure and RNA Channeling to the Exosome Complex.
Cell(Cambridge,Mass.), 154, 2013
4BZJ
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BU of 4bzj by Molmil
The structure of the COPII coat assembled on membranes
Descriptor: Protein transport protein SEC13, Protein transport protein SEC31
Authors:Zanetti, G, Prinz, S, Daum, S, Meister, A, Schekman, R, Bacia, K, Briggs, J.A.G.
Deposit date:2013-07-26
Release date:2013-09-18
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (40 Å)
Cite:The Structure of the Copii Transport-Vesicle Coat Assembled on Membranes
Elife, 2, 2013
4Z28
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BU of 4z28 by Molmil
Crystal structure of short hoefavidin biotin complex
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Avidin family, BIOTIN
Authors:Livnah, O, Avraham, O.
Deposit date:2015-03-29
Release date:2015-07-15
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail.
J.Struct.Biol., 191, 2015
4Z6J
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BU of 4z6j by Molmil
Crystal structure of apo intact hoefavidin
Descriptor: Avidin family
Authors:Livnah, O, Avraham, O.
Deposit date:2015-04-05
Release date:2015-07-15
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail.
J.Struct.Biol., 191, 2015
6S13
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BU of 6s13 by Molmil
Erythromycin Resistant Staphylococcus aureus 70S ribosome (delta R88 A89 uL22).
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A.
Deposit date:2019-06-18
Release date:2019-08-21
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019
4GGD
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BU of 4ggd by Molmil
Structural analysis of human Cdc20 supports multisite degron recognition by APC/C.
Descriptor: Cell division cycle protein 20 homolog, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Authors:Luo, X, Tian, W, Tomchick, D.R.
Deposit date:2012-08-06
Release date:2012-11-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.435 Å)
Cite:Structural analysis of human Cdc20 supports multisite degron recognition by APC/C.
Proc.Natl.Acad.Sci.USA, 109, 2012
6RLQ
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BU of 6rlq by Molmil
CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ45031882
Descriptor: (1~{S},2~{R},3~{S},5~{R})-3-[2-(2-azanyl-3-bromanyl-quinolin-7-yl)ethyl]-5-(4-azanylpyrrolo[2,3-d]pyrimidin-7-yl)cyclop entane-1,2-diol, Methylosome protein 50, Protein arginine N-methyltransferase 5
Authors:Brown, D.G, Robinson, C.M, Pande, V.
Deposit date:2019-05-02
Release date:2020-07-15
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ45031882
To Be Published
6RM3
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BU of 6rm3 by Molmil
Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome
Descriptor: 16S rRNA, 23S rRNA, 5S rRNA, ...
Authors:Barandun, J, Hunziker, M, Vossbrinck, C.R, Klinge, S.
Deposit date:2019-05-05
Release date:2019-07-10
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome.
Nat Microbiol, 4, 2019
4CY1
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BU of 4cy1 by Molmil
Crystal structure of the KANSL1-WDR5 complex.
Descriptor: GLYCEROL, KAT8 REGULATORY NSL COMPLEX SUBUNIT 1, WD REPEAT-CONTAINING PROTEIN 5
Authors:Dias, J, Brettschneider, J, Cusack, S, Kadlec, J.
Deposit date:2014-04-09
Release date:2014-05-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
4CGB
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BU of 4cgb by Molmil
Crystal structure of the trimerization domain of EML2
Descriptor: ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2, GLYCEROL, POTASSIUM ION
Authors:Richards, M.W, Bayliss, R.
Deposit date:2013-11-21
Release date:2014-12-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.154 Å)
Cite:Microtubule Association of Eml Proteins and the Eml4-Alk Variant 3 Oncoprotein Require an N-Terminal Trimerization Domain.
Biochem.J., 467, 2015
6S1L
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BU of 6s1l by Molmil
Structure of fission yeast Mis16
Descriptor: Histone acetyltransferase type B subunit 2
Authors:Lefevre, S, Korntner-Vetter, M, Singleton, M.R.
Deposit date:2019-06-19
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Subunit interactions and arrangements in the fission yeast Mis16-Mis18-Mis19 complex.
Life Sci Alliance, 2, 2019
4GM8
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BU of 4gm8 by Molmil
Crystal structure of human WD repeat domain 5 with compound MM-102
Descriptor: MM-102, WD repeat-containing protein 5
Authors:Karatas, H, Townsend, E.C, Chen, Y, Bernard, D, Cao, F, Liu, L, Lei, M, Dou, Y, Wang, S.
Deposit date:2012-08-15
Release date:2013-07-31
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction.
J.Am.Chem.Soc., 135, 2013
6RXY
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BU of 6rxy by Molmil
Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state a
Descriptor: 35S rRNA, 40S ribosomal protein S13-like protein, 40S ribosomal protein S14-like protein, ...
Authors:Cheng, J, Kellner, N, Griesel, S, Berninghausen, O, Beckmann, R, Hurt, E.
Deposit date:2019-06-10
Release date:2019-08-14
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Mol.Cell, 75, 2019
6RXT
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BU of 6rxt by Molmil
Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state A
Descriptor: 35S ribosomal RNA, 40S ribosomal protein S1, 40S ribosomal protein S13-like protein, ...
Authors:Cheng, J, Kellner, N, Griesel, S, Berninghausen, O, Beckmann, R, Hurt, E.
Deposit date:2019-06-10
Release date:2019-08-14
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Mol.Cell, 75, 2019
6S1R
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BU of 6s1r by Molmil
Structure of fission yeast Mis16 bound to histone H4
Descriptor: Histone H4, Histone acetyltransferase type B subunit 2
Authors:Lefevre, S, Korntner-Vetter, M, Singleton, M.R.
Deposit date:2019-06-19
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Subunit interactions and arrangements in the fission yeast Mis16-Mis18-Mis19 complex.
Life Sci Alliance, 2, 2019
4CY2
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BU of 4cy2 by Molmil
Crystal structure of the KANSL1-WDR5-KANSL2 complex.
Descriptor: KAT8 REGULATORY NSL COMPLEX SUBUNIT 1, KAT8 REGULATORY NSL COMPLEX SUBUNIT 2, WD REPEAT-CONTAINING PROTEIN 5
Authors:Dias, J, Brettschneider, J, Cusack, S, Kadlec, J.
Deposit date:2014-04-09
Release date:2014-05-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
3HAZ
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BU of 3haz by Molmil
Crystal structure of bifunctional proline utilization A (PutA) protein
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Tanner, J.J.
Deposit date:2009-05-03
Release date:2010-02-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the bifunctional proline utilization A flavoenzyme from Bradyrhizobium japonicum
Proc.Natl.Acad.Sci.USA, 107, 2010
4CY3
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BU of 4cy3 by Molmil
Crystal structure of the NSL1-WDS complex.
Descriptor: CG4699, ISOFORM D, GLYCEROL, ...
Authors:Dias, J, Brettschneider, J, Cusack, S, Kadlec, J.
Deposit date:2014-04-10
Release date:2014-05-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
4GQB
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BU of 4gqb by Molmil
Crystal Structure of the human PRMT5:MEP50 Complex
Descriptor: (2S,5S,6E)-2,5-diamino-6-[(3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxydihydrofuran-2(3H)-ylidene]hexanoic acid, Histone H4 peptide, Methylosome protein 50, ...
Authors:Antonysamy, S, Bonday, Z, Campbell, R, Doyle, B, Druzina, Z, Gheyi, T, Han, B, Jungheim, L.N, Qian, Y, Rauch, C, Russell, M, Sauder, J.M, Wasserman, S.R, Weichert, K, Willard, F.S, Zhang, A, Emtage, S.
Deposit date:2012-08-22
Release date:2012-10-17
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structure of the human PRMT5:MEP50 complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
8P16
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BU of 8p16 by Molmil
E167K RF2 on E. coli 70S release complex with UGG (Structure I)
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S.
Deposit date:2023-05-11
Release date:2024-05-22
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:The compensatory mechanism of a naturally evolved E167K RF2 counteracting the loss of RF1 in bacteria
To Be Published
4CY5
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BU of 4cy5 by Molmil
Crystal structure of the NSL1-WDS-NSL2 complex.
Descriptor: CG4699, ISOFORM D, DIM GAMMA-TUBULIN 1, ...
Authors:Dias, J, Brettschneider, J, Cusack, S, Kadlec, J.
Deposit date:2014-04-10
Release date:2014-05-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
6S0X
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BU of 6s0x by Molmil
Erythromycin Resistant Staphylococcus aureus 70S ribosome (delta R88 A89 uL22) in complex with erythromycin.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A.
Deposit date:2019-06-18
Release date:2019-08-21
Method:ELECTRON MICROSCOPY (2.425 Å)
Cite:Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019
6RXV
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BU of 6rxv by Molmil
Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state B2
Descriptor: 35S ribosomal RNA, 40S ribosomal protein S1, 40S ribosomal protein S11-like protein, ...
Authors:Cheng, J, Kellner, N, Griesel, S, Berninghausen, O, Beckmann, R, Hurt, E.
Deposit date:2019-06-10
Release date:2019-08-14
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Mol.Cell, 75, 2019

224572

数据于2024-09-04公开中

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