6RLQ

CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ45031882

Summary for 6RLQ

• Entry DOI: 10.2210/pdb6rlq/pdb
• Descriptor: Protein arginine N-methyltransferase 5, Methylosome protein 50, (1~{S},2~{R},3~{S},5~{R})-3-[2-(2-azanyl-3-bromanyl-quinolin-7-yl)ethyl]-5-(4-azanylpyrrolo[2,3-d]pyrimidin-7-yl)cyclop entane-1,2-diol, ... (4 entities in total)
• Functional Keywords: prmt5, mep50, ligand, translocase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 111701.92

Authors

Brown, D.G.,Robinson, C.M.,Pande, V. (deposition date: 2019-05-02, release date: 2020-07-15, Last modification date: 2024-05-15)

• Primary citation: Brown, D.G.,Robinson, C.M.,Pande, V.; CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ45031882; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.53 Å)