6RLQ
CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ45031882
Summary for 6RLQ
Entry DOI | 10.2210/pdb6rlq/pdb |
Descriptor | Protein arginine N-methyltransferase 5, Methylosome protein 50, (1~{S},2~{R},3~{S},5~{R})-3-[2-(2-azanyl-3-bromanyl-quinolin-7-yl)ethyl]-5-(4-azanylpyrrolo[2,3-d]pyrimidin-7-yl)cyclop entane-1,2-diol, ... (4 entities in total) |
Functional Keywords | prmt5, mep50, ligand, translocase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 111701.92 |
Authors | Brown, D.G.,Robinson, C.M.,Pande, V. (deposition date: 2019-05-02, release date: 2020-07-15, Last modification date: 2024-05-15) |
Primary citation | Brown, D.G.,Robinson, C.M.,Pande, V. CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ45031882 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.53 Å) |
Structure validation
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