4GQB
Crystal Structure of the human PRMT5:MEP50 Complex
Summary for 4GQB
Entry DOI | 10.2210/pdb4gqb/pdb |
Descriptor | Protein arginine N-methyltransferase 5, Methylosome protein 50, Histone H4 peptide, ... (5 entities in total) |
Functional Keywords | tim barrel, beta-propeller, methyltransferase, methylation, transferase-protein binding complex, transferase/protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 112155.91 |
Authors | Antonysamy, S.,Bonday, Z.,Campbell, R.,Doyle, B.,Druzina, Z.,Gheyi, T.,Han, B.,Jungheim, L.N.,Qian, Y.,Rauch, C.,Russell, M.,Sauder, J.M.,Wasserman, S.R.,Weichert, K.,Willard, F.S.,Zhang, A.,Emtage, S. (deposition date: 2012-08-22, release date: 2012-10-17, Last modification date: 2018-11-21) |
Primary citation | Antonysamy, S.,Bonday, Z.,Campbell, R.M.,Doyle, B.,Druzina, Z.,Gheyi, T.,Han, B.,Jungheim, L.N.,Qian, Y.,Rauch, C.,Russell, M.,Sauder, J.M.,Wasserman, S.R.,Weichert, K.,Willard, F.S.,Zhang, A.,Emtage, S. Crystal structure of the human PRMT5:MEP50 complex. Proc.Natl.Acad.Sci.USA, 109:17960-17965, 2012 Cited by PubMed: 23071334DOI: 10.1073/pnas.1209814109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.06 Å) |
Structure validation
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