6S0X

Erythromycin Resistant Staphylococcus aureus 70S ribosome (delta R88 A89 uL22) in complex with erythromycin.

This is a large structure.

Summary for 6S0X

EMDB information10076
Descriptor23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ... (53 entities in total)
Functional Keywordsribosome, antibiotics, resistance, staphylococcus aureus, exit tunnel, rna, rproteins, erythromycin
Biological sourceStaphylococcus aureus
Total number of polymer chains52
Total molecular weight2105954.94
Authors
Halfon, Y.,Matozv, D.,Eyal, Z.,Bashan, A.,Zimmerman, E.,Kjeldgaard, J.,Ingmer, H.,Yonath, A. (deposition date: 2019-06-18, release date: 2019-08-21)
Primary citation
Halfon, Y.,Matzov, D.,Eyal, Z.,Bashan, A.,Zimmerman, E.,Kjeldgaard, J.,Ingmer, H.,Yonath, A.
Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9:11460-11460, 2019
PubMed: 31391518 (PDB entries with the same primary citation)
DOI: 10.1038/s41598-019-48019-1
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone13 0.1% 18.2% 0.33MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report