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6P62	HIV Env BG505 NFL TD+ in complex with antibody E70 fragment antigen binding Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env BG505 NFL TD+, ... Authors: Ozorowski, G, Torres, J.L, Ward, A.B. Deposit date: 2019-05-31 Release date: 2019-11-20 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (3.57 Å) Cite: Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity, 51, 2019
7AKD	Structure of the SARS-CoV-2 spike glycoprotein in complex with the 47D11 neutralizing antibody Fab fragment Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 47D11 neutralizing antibody heavy chain, ... Authors: Fedry, J, Hurdiss, D.L, Wang, C, Li, W, Obal, G, Drulyte, I, Howes, S.C, van Kuppeveld, F.J.M, Foerster, F, Bosch, B.J. Deposit date: 2020-09-30 Release date: 2021-05-19 Last modified: 2021-06-16 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11. Sci Adv, 7, 2021
7AKJ	Structure of the SARS-CoV spike glycoprotein in complex with the 47D11 neutralizing antibody Fab fragment Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Fedry, J, Hurdiss, D.L, Wang, C, Li, W, Obal, G, Drulyte, I, Howes, S.C, van Kuppeveld, F.J.M, Foerster, F, Bosch, B.J. Deposit date: 2020-10-01 Release date: 2021-05-19 Last modified: 2021-06-16 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11. Sci Adv, 7, 2021
4OLZ	Crystal structure of antibody VRC07-G54W in complex with clade A/E 93TH057 HIV-1 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... Authors: Kwon, Y.D, Kwong, P.D. Deposit date: 2014-01-25 Release date: 2014-09-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
7PI7	PfCyRPA bound to monoclonal antibody Cy.002 Fab fragment Descriptor: Cysteine-rich protective antigen, Monoclonal antibody Cy.002 heavy chain, Monoclonal antibody Cy.002 light chain Authors: Ragotte, R.J, Higgins, M.K. Deposit date: 2021-08-19 Release date: 2022-02-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.72 Å) Cite: Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
7PHW	PfCyRPA bound to monoclonal antibody Cy.004 Fab fragment Descriptor: CALCIUM ION, Cysteine-rich protective antigen, Monoclonal antibody Cy.004 heavy chain, ... Authors: Ragotte, R.J, Higgins, M.K. Deposit date: 2021-08-18 Release date: 2022-02-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.793 Å) Cite: Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
7PHV	PfCyRPA bound to monoclonal antibody Cy.007 Fab fragment Descriptor: AMMONIUM ION, Cysteine-rich protective antigen, Monoclonal antibody Cy.007 heavy chain, ... Authors: Ragotte, R.J, Higgins, M.K. Deposit date: 2021-08-18 Release date: 2022-02-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.091 Å) Cite: Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
7PI2	PfCyRPA bound to monoclonal antibody Cy.003 Fab fragment Descriptor: Cysteine-rich protective antigen, Monoclonal antibody Cy.003 heavy chain, Monoclonal antibody Cy.003 light chain Authors: Ragotte, R.J, Higgins, M.K. Deposit date: 2021-08-19 Release date: 2022-02-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.14 Å) Cite: Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
3GKW	Crystal structure of the Fab fragment of Nimotuzumab. An anti-epidermal growth factor receptor antibody Descriptor: DI(HYDROXYETHYL)ETHER, Heavy chain of the antibody Nimotuzumab, Light chain of the antibody Nimotuzumab, ... Authors: Talavera, A, Friemann, R, Martinez-Fleites, C, Moreno, E, Krengel, U. Deposit date: 2009-03-11 Release date: 2009-08-04 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Nimotuzumab, an antitumor antibody that targets the epidermal growth factor receptor, blocks ligand binding while permitting the active receptor conformation Cancer Res., 69, 2009
6P65	HIV Env 16055 NFL TD 2CC+ in complex with antibody 1C2 fragment antigen binding Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Ozorowski, G, Torres, J.L, Ward, A.B. Deposit date: 2019-05-31 Release date: 2019-11-20 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (3.94 Å) Cite: Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity, 51, 2019
5BZW	Crystal Structure of PCDN-27B, an antibody from the PCDN family of HIV-1 antibodies Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B3 HIV Antibody heavy chain, 2B3 HIV Antibody light chain, ... Authors: Garces, F, WILSON, I.A. Deposit date: 2015-06-11 Release date: 2016-05-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch. Immunity, 44, 2016
4G6M	Crystal structure of human IL-1beta in complex with therapeutic antibody binding fragment of gevokizumab Descriptor: Interleukin-1 beta, heavy chain of gevokizumab antibody binding fragment, light chain of gevokizumab antibody binding fragment Authors: Blech, M, Hoerer, S. Deposit date: 2012-07-19 Release date: 2012-12-19 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Crystal structure of human IL-1beta in complex with therapeutic antibody binding fragment of gevokizumab J.Mol.Biol., 425, 2013
1CQK	CRYSTAL STRUCTURE OF THE CH3 DOMAIN FROM THE MAK33 ANTIBODY Descriptor: CH3 DOMAIN OF MAK33 ANTIBODY Authors: Thies, M.J, Mayer, J, Augustine, J.G, Frederick, C.A, Lilie, H, Buchner, J. Deposit date: 1999-08-06 Release date: 1999-09-11 Last modified: 2018-08-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Folding and association of the antibody domain CH3: prolyl isomerization preceeds dimerization. J.Mol.Biol., 293, 1999
5CEY	Crystal Structure of Fab 9H+3L, a putative precursor of the PGT121 family of potent HIV-1 antibodies Descriptor: 1-DEOXY-1-THIO-HEPTAETHYLENE GLYCOL, Antibody 9H+3L Fab heavy chain, Antibody 9H+3L Fab light chain, ... Authors: Wilson, I.A, Garces, F. Deposit date: 2015-07-07 Release date: 2015-12-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.387 Å) Cite: Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans. Immunity, 43, 2015
4FQR	Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly neutralizing antibody C05, ... Authors: Ekiert, D.C, Wilson, I.A. Deposit date: 2012-06-25 Release date: 2012-09-19 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (4.1 Å) Cite: Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature, 489, 2012
4FNL	Crystal structure of broadly neutralizing antibody C05 Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Antibody C05, Heavy Chain, ... Authors: Ekiert, D.C, Wilson, I.A. Deposit date: 2012-06-19 Release date: 2012-09-19 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.297 Å) Cite: Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature, 489, 2012
5FV1	Crystal structure of hVEGF in complex with VK domain antibody Descriptor: VASCULAR ENDOTHELIAL GROWTH FACTOR A, VK DOMAIN ANTIBODY Authors: Chung, C, Walker, A. Deposit date: 2016-02-02 Release date: 2016-02-17 Last modified: 2019-05-15 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Novel Interaction Mechanism of a Domain Antibody Based Inhibitor of Human Vascular Endothelial Growth Factor with Greater Potency Than Ranibizumab and Bevacizumab and Improved Capacity Over Aflibercept. J.Biol.Chem., 291, 2016
4FP8	Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin, HA1 subunit Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C05, ... Authors: Ekiert, D.C, Wilson, I.A. Deposit date: 2012-06-21 Release date: 2012-09-19 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.947 Å) Cite: Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature, 489, 2012
1RI8	Crystal Structure of the Camelid Single Domain Antibody 1D2L19 in complex with Hen Egg White Lysozyme Descriptor: GLYCEROL, Lysozyme C, camelid ANTIBODY HEAVY CHAIN Authors: De Genst, E, Silence, K, Ghahroudi, M.A, Decanniere, K, Loris, R, Kinne, J, Wyns, L, Muyldermans, S. Deposit date: 2003-11-17 Release date: 2005-02-01 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires. J.Biol.Chem., 280, 2005
6OZ2	Crystal structure of the broadly neutralizing antibody N49P6 Fab in complex with HIV-1 Clade A/E strain 93TH057 gp120 core. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N49P6 antibody Fab heavy chain, N49P6 antibody Fab light chain, ... Authors: Tolbert, W.D, Pazgier, M. Deposit date: 2019-05-15 Release date: 2020-08-19 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Near-Pan-neutralizing, Plasma Deconvoluted Antibody N49P6 Mimics Host Receptor CD4 in Its Quaternary Interactions with the HIV-1 Envelope Trimer. Mbio, 2021
4OII	West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab Descriptor: Heavy Chain of Fab fragment of 22NS1 Antibody, Light Chain of Fab fragment of 22NS1 Antibody, NON-STRUCTURAL PROTEIN NS1 Authors: Edeling, M.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2014-01-19 Release date: 2014-03-05 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis of Flavivirus NS1 assembly and antibody recognition. Proc.Natl.Acad.Sci.USA, 111, 2014
3LN9	Crystal structure of the fibril-specific B10 antibody fragment Descriptor: CITRATE ANION, GLYCEROL, Immunoglobulin heavy chain antibody variable domain B10, ... Authors: Parthier, C, Morgado, I, Stubbs, M.T, Faendrich, M. Deposit date: 2010-02-02 Release date: 2010-12-15 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Amyloid Fibril Recognition with the Conformational B10 Antibody Fragment Depends on Electrostatic Interactions. J.Mol.Biol., 2010
5ZV3	Crystal structure of human anti-tau antibody CBTAU-28.1 in complex with its tau peptide Descriptor: Heavy chain of antibody CBTAU28.1, Light chain (kappa) of antibody CBTAU28.1, Peptide from Microtubule-associated protein tau Authors: Zhang, H, Wilson, I.A. Deposit date: 2018-05-09 Release date: 2018-06-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.093 Å) Cite: A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities. Acta Neuropathol Commun, 6, 2018
5FV2	Crystal structure of hVEGF in complex with VH domain antibody Descriptor: VASCULAR ENDOTHELIAL GROWTH FACTOR, VH DOMAIN ANTIBODY Authors: Chung, C, Batuwangala, T. Deposit date: 2016-02-02 Release date: 2016-02-17 Last modified: 2019-05-15 Method: X-RAY DIFFRACTION (3.45 Å) Cite: Novel Interaction Mechanism of a Domain Antibody Based Inhibitor of Human Vascular Endothelial Growth Factor with Greater Potency Than Ranibizumab and Bevacizumab and Improved Capacity Over Aflibercept. J.Biol.Chem., 291, 2016
5H2B	Structure of a novel antibody G196 Descriptor: G196 antibody Heavy chain, G196 antibody Light chain Authors: Park, S.Y, Sugiyama, K. Deposit date: 2016-10-14 Release date: 2017-03-22 Last modified: 2020-02-26 Method: X-RAY DIFFRACTION (2.001 Å) Cite: G196 epitope tag system: a novel monoclonal antibody, G196, recognizes the small, soluble peptide DLVPR with high affinity. Sci Rep, 7, 2017

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