Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

8UUC
DownloadVisualize
BU of 8uuc by Molmil
Crystal structure of a bacterial clusterless MutYX bound to an Abasic site analog (THF) opposite d(8-oxo-G)
Descriptor: 1,2-ETHANEDIOL, Adenine DNA glycosylase, CHLORIDE ION, ...
Authors:Trasvina-Arenas, C.H, David, S.S, Fisher, A.J.
Deposit date:2023-11-01
Release date:2025-01-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of MutYX: A novel clusterless adenine DNA glycosylase with a distinct C-terminal domain and 8-Oxoguanine recognition sphere.
Biorxiv, 2025
5KTF
DownloadVisualize
BU of 5ktf by Molmil
Structure of the C-terminal transmembrane domain of scavenger receptor BI (SR-BI)
Descriptor: Scavenger receptor class B member 1
Authors:Chadwick, A.C, Peterson, F.C, Volkman, B.F, Sahoo, D.
Deposit date:2016-07-11
Release date:2017-03-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR Structure of the C-Terminal Transmembrane Domain of the HDL Receptor, SR-BI, and a Functionally Relevant Leucine Zipper Motif.
Structure, 25, 2017
6XKC
DownloadVisualize
BU of 6xkc by Molmil
Crystal structure of E3 ligase
Descriptor: Protein fem-1 homolog C
Authors:Yan, X, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Dong, C, Structural Genomics Consortium (SGC)
Deposit date:2020-06-26
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Molecular basis for ubiquitin ligase CRL2 FEM1C -mediated recognition of C-degron.
Nat.Chem.Biol., 17, 2021
4WQ8
DownloadVisualize
BU of 4wq8 by Molmil
Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - tetrathionate soak
Descriptor: HEME C, IODIDE ION, SULFATE ION, ...
Authors:Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M.
Deposit date:2014-10-21
Release date:2015-02-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.3989 Å)
Cite:Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION.
J.Biol.Chem., 290, 2015
6ACB
DownloadVisualize
BU of 6acb by Molmil
Crystal structure of PDE5 in complex with inhibitor LW1805
Descriptor: 3-[(2H-1,3-benzodioxol-5-yl)methyl]-8-fluoro-6-{[2-(4-methylpiperazin-1-yl)ethyl]amino}-1-(1,3-thiazol-2-yl)[1]benzopyrano[2,3-c]pyrrol-9(2H)-one, MAGNESIUM ION, SULFATE ION, ...
Authors:Wu, D, Huang, Y.D, Huang, Y.Y, Luo, H.B.
Deposit date:2018-07-26
Release date:2018-09-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Optimization of Chromeno[2,3- c]pyrrol-9(2 H)-ones as Highly Potent, Selective, and Orally Bioavailable PDE5 Inhibitors: Structure-Activity Relationship, X-ray Crystal Structure, and Pharmacodynamic Effect on Pulmonary Arterial Hypertension.
J. Med. Chem., 61, 2018
7SYJ
DownloadVisualize
BU of 7syj by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 4(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYX
DownloadVisualize
BU of 7syx by Molmil
Structure of the delta dII IRES eIF5B-containing 48S initiation complex, closed conformation. Structure 15(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S24, 40S ribosomal protein S25, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYN
DownloadVisualize
BU of 7syn by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 8(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S2, HCV IRES, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA
To Be Published
7SYW
DownloadVisualize
BU of 7syw by Molmil
Structure of the wt IRES eIF5B-containing 48S initiation complex, closed conformation. Structure 15(wt)
Descriptor: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYL
DownloadVisualize
BU of 7syl by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, closed conformation. Structure 6(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYK
DownloadVisualize
BU of 7syk by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 5(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYI
DownloadVisualize
BU of 7syi by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 3(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
9CLO
DownloadVisualize
BU of 9clo by Molmil
DosP R97A with c-di-GMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Oxygen sensor protein DosP, ...
Authors:Kumar, P, Kober, D.L.
Deposit date:2024-07-11
Release date:2024-11-20
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of the multi-domain oxygen sensor DosP: remote control of a c-di-GMP phosphodiesterase by a regulatory PAS domain.
Nat Commun, 15, 2024
7SYU
DownloadVisualize
BU of 7syu by Molmil
Structure of the delta dII IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYT
DownloadVisualize
BU of 7syt by Molmil
Structure of the wt IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(wt)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYV
DownloadVisualize
BU of 7syv by Molmil
Structure of the wt IRES eIF5B-containing pre-48S initiation complex, open conformation. Structure 14(wt)
Descriptor: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-20
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
4WQ9
DownloadVisualize
BU of 4wq9 by Molmil
Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - dithionite soak
Descriptor: 1,2-ETHANEDIOL, HEME C, HYDROSULFURIC ACID, ...
Authors:Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M.
Deposit date:2014-10-21
Release date:2015-02-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION.
J.Biol.Chem., 290, 2015
4OOW
DownloadVisualize
BU of 4oow by Molmil
HCV NS5B polymerase with a fragment of quercetagetin
Descriptor: CATECHOL, RNA-directed RNA polymerase
Authors:Guichou, J.F, Ahmed-Belkacem, A, Rozenn, B, Nazim, N, Hernandez, E, Pallier, C, Pawlotsky, J.M.
Deposit date:2014-02-04
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Inhibition of RNA binding to hepatitis C virus RNA-dependent RNA polymerase: a new mechanism for antiviral intervention.
Nucleic Acids Res., 42, 2014
4WQD
DownloadVisualize
BU of 4wqd by Molmil
Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - K208G mutant
Descriptor: 1,2-ETHANEDIOL, GUANIDINE, HEME C, ...
Authors:Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M.
Deposit date:2014-10-21
Release date:2015-02-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION.
J.Biol.Chem., 290, 2015
7U2V
DownloadVisualize
BU of 7u2v by Molmil
Plasmodium falciparum Cyt c2 DSD
Descriptor: Cytochrome c2, HEME C
Authors:Hill, C.P, Wienkers, H.J, Whitby, F.G.
Deposit date:2022-02-24
Release date:2023-05-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Direct tests of cytochrome c and c1 functions in the electron transport chain of malaria parasites
Proc Natl Acad Sci U S A, 120, 2023
2X4A
DownloadVisualize
BU of 2x4a by Molmil
Crystal structure of the C-terminal domain of InvA
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, INVASION PROTEIN INVA, PHOSPHATE ION
Authors:Worrall, L.J, Vuckovic, M, Strynadka, N.C.J.
Deposit date:2010-01-28
Release date:2010-05-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Crystal Structure of the C-Terminal Domain of the Salmonella Type III Secretion System Export Apparatus Protein Inva.
Protein Sci., 19, 2010
8FG0
DownloadVisualize
BU of 8fg0 by Molmil
Crystal structure of the 3764 Fab in complex with the C-terminal PfCSP linker, PfCSP281-294.
Descriptor: 3764 Fab Heavy chain, 3764 Fab Light chain, Circumsporozoite protein
Authors:Burn Aschner, C, Julien, J.P.
Deposit date:2022-12-11
Release date:2023-05-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Molecular and functional properties of human Plasmodium falciparum CSP C-terminus antibodies.
Embo Mol Med, 15, 2023
7KO6
DownloadVisualize
BU of 7ko6 by Molmil
C1B domain of Protein kinase C in complex with ingenol-3-angelate and phosphocholine
Descriptor: (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, Protein kinase C delta type, ZINC ION, ...
Authors:Katti, S.S, Krieger, I.V.
Deposit date:2020-11-06
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists.
Nat Commun, 13, 2022
7KNJ
DownloadVisualize
BU of 7knj by Molmil
C1B domain of Protein kinase C in complex with Phorbol ester and Phosphatidylcholine
Descriptor: (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, Phorbol 12,13-dibutyrate, Protein kinase C delta type, ...
Authors:Katti, S.S, Krieger, I.
Deposit date:2020-11-04
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists.
Nat Commun, 13, 2022
5UOY
DownloadVisualize
BU of 5uoy by Molmil
Crystal structure of human PDE1B catalytic domain in complex with inhibitor 16j (6-(4-Methoxybenzyl)-9-((tetrahydro-2H-pyran-4-yl)methyl)-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one)
Descriptor: 6-[(4-methoxyphenyl)methyl]-9-[(oxan-4-yl)methyl]-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one, Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, MAGNESIUM ION, ...
Authors:Cedervall, E.P, Allerston, C.K, Xu, R, Sridhar, V, Barker, R, Aertgeerts, K.
Deposit date:2017-02-01
Release date:2017-04-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties.
J. Med. Chem., 60, 2017

238582

数据于2025-07-09公开中

PDB statisticsPDBj update infoContact PDBjnumon