7SYV

Structure of the wt IRES eIF5B-containing pre-48S initiation complex, open conformation. Structure 14(wt)

Summary for 7SYV

Entry DOI	10.2210/pdb7syv/pdb
EMDB information	25542
Descriptor	18S rRNA, eS28, uS3, ... (43 entities in total)
Functional Keywords	hcv, ires, 40s, ribosome
Biological source	hepatitis C virus genotype 1a More
Total number of polymer chains	39
Total formula weight	1501861.66
Authors	Brown, Z.P.,Abaeva, I.S.,De, S.,Hellen, C.U.T.,Pestova, T.V.,Frank, J. (deposition date: 2021-11-25, release date: 2022-07-20, Last modification date: 2023-02-01)
Primary citation	Brown, Z.P.,Abaeva, I.S.,De, S.,Hellen, C.U.T.,Pestova, T.V.,Frank, J. Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41:e110581-e110581, 2022 Cited by PubMed: 35822879 DOI: 10.15252/embj.2022110581 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation