7SYV

Structure of the wt IRES eIF5B-containing pre-48S initiation complex, open conformation. Structure 14(wt)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0003723	molecular_function	RNA binding
A	0003743	molecular_function	translation initiation factor activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006413	biological_process	translational initiation
A	0008135	molecular_function	translation factor activity, RNA binding
A	0016282	cellular_component	eukaryotic 43S preinitiation complex
A	0033290	cellular_component	eukaryotic 48S preinitiation complex
A	0042255	biological_process	ribosome assembly
A	0043614	cellular_component	multi-eIF complex
B	0000028	biological_process	ribosomal small subunit assembly
B	0001618	molecular_function	virus receptor activity
B	0002181	biological_process	cytoplasmic translation
B	0003735	molecular_function	structural constituent of ribosome
B	0005055	molecular_function	laminin receptor activity
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005840	cellular_component	ribosome
B	0005886	cellular_component	plasma membrane
B	0006412	biological_process	translation
B	0007155	biological_process	cell adhesion
B	0015935	cellular_component	small ribosomal subunit
B	0022627	cellular_component	cytosolic small ribosomal subunit
B	0030686	cellular_component	90S preribosome
B	0043236	molecular_function	laminin binding
B	0046718	biological_process	symbiont entry into host cell
B	1990904	cellular_component	ribonucleoprotein complex
C	0003735	molecular_function	structural constituent of ribosome
C	0005634	cellular_component	nucleus
C	0005730	cellular_component	nucleolus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
C	0022627	cellular_component	cytosolic small ribosomal subunit
C	0030154	biological_process	cell differentiation
C	1990904	cellular_component	ribonucleoprotein complex
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0015935	cellular_component	small ribosomal subunit
E	0003677	molecular_function	DNA binding
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
E	0005634	cellular_component	nucleus
E	0005730	cellular_component	nucleolus
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0005819	cellular_component	spindle
E	0005840	cellular_component	ribosome
E	0005856	cellular_component	cytoskeleton
E	0006281	biological_process	DNA repair
E	0006412	biological_process	translation
E	0006417	biological_process	regulation of translation
E	0006915	biological_process	apoptotic process
E	0015935	cellular_component	small ribosomal subunit
E	0016829	molecular_function	lyase activity
E	0022626	cellular_component	cytosolic ribosome
E	0022627	cellular_component	cytosolic small ribosomal subunit
E	0031334	biological_process	positive regulation of protein-containing complex assembly
E	0045202	cellular_component	synapse
E	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
E	0051301	biological_process	cell division
E	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E	1990904	cellular_component	ribonucleoprotein complex
E	2001235	biological_process	positive regulation of apoptotic signaling pathway
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0019843	molecular_function	rRNA binding
F	0022627	cellular_component	cytosolic small ribosomal subunit
F	1990904	cellular_component	ribonucleoprotein complex
G	0000028	biological_process	ribosomal small subunit assembly
G	0003723	molecular_function	RNA binding
G	0003729	molecular_function	mRNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005634	cellular_component	nucleus
G	0005730	cellular_component	nucleolus
G	0005737	cellular_component	cytoplasm
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0015935	cellular_component	small ribosomal subunit
G	0019843	molecular_function	rRNA binding
G	0022626	cellular_component	cytosolic ribosome
G	0022627	cellular_component	cytosolic small ribosomal subunit
G	1990904	cellular_component	ribonucleoprotein complex
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	1990904	cellular_component	ribonucleoprotein complex
I	0003735	molecular_function	structural constituent of ribosome
I	0005634	cellular_component	nucleus
I	0005730	cellular_component	nucleolus
I	0005737	cellular_component	cytoplasm
I	0005813	cellular_component	centrosome
I	0005840	cellular_component	ribosome
I	0005856	cellular_component	cytoskeleton
I	0006364	biological_process	rRNA processing
I	0006412	biological_process	translation
I	0022626	cellular_component	cytosolic ribosome
I	0022627	cellular_component	cytosolic small ribosomal subunit
I	0030686	cellular_component	90S preribosome
I	0032040	cellular_component	small-subunit processome
I	0042274	biological_process	ribosomal small subunit biogenesis
I	1990904	cellular_component	ribonucleoprotein complex
J	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J	0003735	molecular_function	structural constituent of ribosome
J	0005634	cellular_component	nucleus
J	0005730	cellular_component	nucleolus
J	0005737	cellular_component	cytoplasm
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0016020	cellular_component	membrane
J	0022626	cellular_component	cytosolic ribosome
J	0022627	cellular_component	cytosolic small ribosomal subunit
J	1990904	cellular_component	ribonucleoprotein complex
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005634	cellular_component	nucleus
K	0005730	cellular_component	nucleolus
K	0005737	cellular_component	cytoplasm
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0015935	cellular_component	small ribosomal subunit
K	0019843	molecular_function	rRNA binding
K	0022626	cellular_component	cytosolic ribosome
K	0022627	cellular_component	cytosolic small ribosomal subunit
K	0042274	biological_process	ribosomal small subunit biogenesis
K	0043226	cellular_component	organelle
K	1990904	cellular_component	ribonucleoprotein complex
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005634	cellular_component	nucleus
L	0022627	cellular_component	cytosolic small ribosomal subunit
M	0003735	molecular_function	structural constituent of ribosome
M	0005634	cellular_component	nucleus
M	0005730	cellular_component	nucleolus
M	0005737	cellular_component	cytoplasm
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0019843	molecular_function	rRNA binding
M	0022626	cellular_component	cytosolic ribosome
M	0022627	cellular_component	cytosolic small ribosomal subunit
M	1990904	cellular_component	ribonucleoprotein complex
N	0003735	molecular_function	structural constituent of ribosome
N	0005634	cellular_component	nucleus
N	0005730	cellular_component	nucleolus
N	0005737	cellular_component	cytoplasm
N	0005794	cellular_component	Golgi apparatus
N	0005829	cellular_component	cytosol
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0022626	cellular_component	cytosolic ribosome
N	0022627	cellular_component	cytosolic small ribosomal subunit
N	0032040	cellular_component	small-subunit processome
N	0042274	biological_process	ribosomal small subunit biogenesis
N	0043231	cellular_component	intracellular membrane-bounded organelle
N	0090263	biological_process	positive regulation of canonical Wnt signaling pathway
N	1990904	cellular_component	ribonucleoprotein complex
O	0003735	molecular_function	structural constituent of ribosome
O	0005634	cellular_component	nucleus
O	0005730	cellular_component	nucleolus
O	0005737	cellular_component	cytoplasm
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0022626	cellular_component	cytosolic ribosome
O	0022627	cellular_component	cytosolic small ribosomal subunit
O	0070181	molecular_function	small ribosomal subunit rRNA binding
O	1990904	cellular_component	ribonucleoprotein complex
P	0000028	biological_process	ribosomal small subunit assembly
P	0003735	molecular_function	structural constituent of ribosome
P	0005634	cellular_component	nucleus
P	0005730	cellular_component	nucleolus
P	0005737	cellular_component	cytoplasm
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0015935	cellular_component	small ribosomal subunit
P	0022627	cellular_component	cytosolic small ribosomal subunit
P	1990904	cellular_component	ribonucleoprotein complex
Q	0000028	biological_process	ribosomal small subunit assembly
Q	0000056	biological_process	ribosomal small subunit export from nucleus
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005737	cellular_component	cytoplasm
Q	0005840	cellular_component	ribosome
Q	0006364	biological_process	rRNA processing
Q	0006412	biological_process	translation
Q	0015935	cellular_component	small ribosomal subunit
Q	0022626	cellular_component	cytosolic ribosome
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	0042274	biological_process	ribosomal small subunit biogenesis
Q	0097371	molecular_function	MDM2/MDM4 family protein binding
Q	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
Q	1990904	cellular_component	ribonucleoprotein complex
Q	1990948	molecular_function	ubiquitin ligase inhibitor activity
R	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005634	cellular_component	nucleus
R	0005730	cellular_component	nucleolus
R	0005737	cellular_component	cytoplasm
R	0005840	cellular_component	ribosome
R	0006364	biological_process	rRNA processing
R	0006412	biological_process	translation
R	0022626	cellular_component	cytosolic ribosome
R	0022627	cellular_component	cytosolic small ribosomal subunit
R	0032040	cellular_component	small-subunit processome
R	0042274	biological_process	ribosomal small subunit biogenesis
R	0045202	cellular_component	synapse
R	1990830	biological_process	cellular response to leukemia inhibitory factor
R	1990904	cellular_component	ribonucleoprotein complex
S	0003735	molecular_function	structural constituent of ribosome
S	0005634	cellular_component	nucleus
S	0005730	cellular_component	nucleolus
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0022626	cellular_component	cytosolic ribosome
S	1990904	cellular_component	ribonucleoprotein complex
T	0003676	molecular_function	nucleic acid binding
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0015935	cellular_component	small ribosomal subunit
T	0019843	molecular_function	rRNA binding
T	0022626	cellular_component	cytosolic ribosome
T	1990904	cellular_component	ribonucleoprotein complex
U	0000028	biological_process	ribosomal small subunit assembly
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005634	cellular_component	nucleus
U	0005730	cellular_component	nucleolus
U	0005737	cellular_component	cytoplasm
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0022626	cellular_component	cytosolic ribosome
U	0022627	cellular_component	cytosolic small ribosomal subunit
U	1990904	cellular_component	ribonucleoprotein complex
V	0003723	molecular_function	RNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005737	cellular_component	cytoplasm
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0015935	cellular_component	small ribosomal subunit
V	0022626	cellular_component	cytosolic ribosome
V	0022627	cellular_component	cytosolic small ribosomal subunit
V	1990904	cellular_component	ribonucleoprotein complex
W	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
W	0000461	biological_process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
W	0002181	biological_process	cytoplasmic translation
W	0003735	molecular_function	structural constituent of ribosome
W	0005737	cellular_component	cytoplasm
W	0005783	cellular_component	endoplasmic reticulum
W	0005791	cellular_component	rough endoplasmic reticulum
W	0005829	cellular_component	cytosol
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0022626	cellular_component	cytosolic ribosome
W	0022627	cellular_component	cytosolic small ribosomal subunit
W	1990904	cellular_component	ribonucleoprotein complex
X	0003735	molecular_function	structural constituent of ribosome
X	0005634	cellular_component	nucleus
X	0005730	cellular_component	nucleolus
X	0005737	cellular_component	cytoplasm
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0022626	cellular_component	cytosolic ribosome
X	0022627	cellular_component	cytosolic small ribosomal subunit
X	1990904	cellular_component	ribonucleoprotein complex
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005634	cellular_component	nucleus
Y	0005730	cellular_component	nucleolus
Y	0005737	cellular_component	cytoplasm
Y	0005783	cellular_component	endoplasmic reticulum
Y	0005791	cellular_component	rough endoplasmic reticulum
Y	0005829	cellular_component	cytosol
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0015935	cellular_component	small ribosomal subunit
Y	0022626	cellular_component	cytosolic ribosome
Y	0022627	cellular_component	cytosolic small ribosomal subunit
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
Z	0044391	cellular_component	ribosomal subunit
Z	1990904	cellular_component	ribonucleoprotein complex
a	0003735	molecular_function	structural constituent of ribosome
a	0005634	cellular_component	nucleus
a	0005730	cellular_component	nucleolus
a	0005737	cellular_component	cytoplasm
a	0005840	cellular_component	ribosome
a	0006364	biological_process	rRNA processing
a	0014069	cellular_component	postsynaptic density
a	0022626	cellular_component	cytosolic ribosome
a	0022627	cellular_component	cytosolic small ribosomal subunit
a	0042274	biological_process	ribosomal small subunit biogenesis
a	0045202	cellular_component	synapse
a	1990904	cellular_component	ribonucleoprotein complex
b	0003735	molecular_function	structural constituent of ribosome
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
c	0000028	biological_process	ribosomal small subunit assembly
c	0003723	molecular_function	RNA binding
c	0003735	molecular_function	structural constituent of ribosome
c	0005634	cellular_component	nucleus
c	0005730	cellular_component	nucleolus
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0022626	cellular_component	cytosolic ribosome
c	0022627	cellular_component	cytosolic small ribosomal subunit
c	0046872	molecular_function	metal ion binding
c	1990904	cellular_component	ribonucleoprotein complex
d	0000028	biological_process	ribosomal small subunit assembly
d	0002181	biological_process	cytoplasmic translation
d	0003735	molecular_function	structural constituent of ribosome
d	0005634	cellular_component	nucleus
d	0005730	cellular_component	nucleolus
d	0005737	cellular_component	cytoplasm
d	0005783	cellular_component	endoplasmic reticulum
d	0005791	cellular_component	rough endoplasmic reticulum
d	0005829	cellular_component	cytosol
d	0005840	cellular_component	ribosome
d	0006364	biological_process	rRNA processing
d	0006412	biological_process	translation
d	0022626	cellular_component	cytosolic ribosome
d	0022627	cellular_component	cytosolic small ribosomal subunit
d	0030490	biological_process	maturation of SSU-rRNA
d	0032040	cellular_component	small-subunit processome
d	0042254	biological_process	ribosome biogenesis
d	0042274	biological_process	ribosomal small subunit biogenesis
d	0045202	cellular_component	synapse
d	1990904	cellular_component	ribonucleoprotein complex
e	0003735	molecular_function	structural constituent of ribosome
e	0005737	cellular_component	cytoplasm
e	0005783	cellular_component	endoplasmic reticulum
e	0005791	cellular_component	rough endoplasmic reticulum
e	0005829	cellular_component	cytosol
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
e	0008270	molecular_function	zinc ion binding
e	0022626	cellular_component	cytosolic ribosome
e	0022627	cellular_component	cytosolic small ribosomal subunit
e	0046872	molecular_function	metal ion binding
e	1990904	cellular_component	ribonucleoprotein complex
f	0003735	molecular_function	structural constituent of ribosome
f	0005634	cellular_component	nucleus
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
f	0022627	cellular_component	cytosolic small ribosomal subunit
f	1990904	cellular_component	ribonucleoprotein complex
g	0003735	molecular_function	structural constituent of ribosome
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
h	0001891	cellular_component	phagocytic cup
h	0001934	biological_process	positive regulation of protein phosphorylation
h	0005080	molecular_function	protein kinase C binding
h	0005634	cellular_component	nucleus
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0005840	cellular_component	ribosome
h	0005886	cellular_component	plasma membrane
h	0006417	biological_process	regulation of translation
h	0006915	biological_process	apoptotic process
h	0007369	biological_process	gastrulation
h	0030425	cellular_component	dendrite
h	0042995	cellular_component	cell projection
h	0043022	molecular_function	ribosome binding
h	0043204	cellular_component	perikaryon
h	0045182	molecular_function	translation regulator activity
h	0048471	cellular_component	perinuclear region of cytoplasm
h	0048511	biological_process	rhythmic process
h	0072344	biological_process	rescue of stalled ribosome
h	1990904	cellular_component	ribonucleoprotein complex
n	0003735	molecular_function	structural constituent of ribosome
n	0005737	cellular_component	cytoplasm
n	0005840	cellular_component	ribosome
n	0006412	biological_process	translation
n	1990904	cellular_component	ribonucleoprotein complex
x	0003924	molecular_function	GTPase activity
x	0005525	molecular_function	GTP binding

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsMMmhgrnnGKKlmtvrIVkhA

Chain	Residue	Details
G	GLU70-ALA96

---

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GfiVLTTSaGIMdheeAR

Chain	Residue	Details
X	GLY100-ARG117

---

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GMkIgrieDvTPiPSD

Chain	Residue	Details
P	LEU116-ASP138

---

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
Y	LYS60-ARG67

---

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgEcRPLS

Chain	Residue	Details
M	GLY123-SER135

---

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KahVaSlegIApedQvVLLaGtpleD

Chain	Residue	Details
f	LYS24-ASP49

---

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKtfnqveIkpemIGhyLGEFsiT

Chain	Residue	Details
Q	ASN98-THR122

---

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvAQiyAirqSiSKAL

Chain	Residue	Details
R	GLY74-LEU92

---

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkekNLkvkGPVrMPT

Chain	Residue	Details
V	ALA43-THR58

---

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY

Chain	Residue	Details
O	VAL98-TYR128

---

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsnrhglirkyg.LNMCRqCFR

Chain	Residue	Details
e	ARG22-ARG44

---

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRVAaPkhWmLdK

Chain	Residue	Details
F	HIS8-LYS22

---

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKTtGFGmIYDSldyakknE

Chain	Residue	Details
Z	PHE64-GLU86

---

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfvdGlMihSgdpVnyyVDtavrhvlLrqGvlG

Chain	Residue	Details
E	ALA147-GLY183

---

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM

Chain	Residue	Details
H	ILE52-MET63

---

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAfvAIGDyn.GhVGlGvkcsk.EVat.AI

Chain	Residue	Details
D	GLY119-ILE151

---

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PshfsrgSksVaRrVLQaLE

Chain	Residue	Details
U	PRO89-GLU108

---

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVFKlglAkSihhARvLI

Chain	Residue	Details
K	LEU106-ILE130

---

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHfwGlrVRGQ

Chain	Residue	Details
T	ARG121-GLN134

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSGswDgTLRLWDL

Chain	Residue	Details
h	ALA78-LEU92
h	ILE120-THR134
h	ILE165-LEU179
h	CYS207-LEU221

---

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IpSKkLRNkIAGYvTH

Chain	Residue	Details
S	ILE41-HIS56

---

site_id	PS00733
Number of Residues	8
Details	RIBOSOMAL_S26E Ribosomal protein S26e signature. YCVSCAIH

Chain	Residue	Details
b	TYR73-HIS80

---

site_id	PS00948
Number of Residues	14
Details	RIBOSOMAL_S7E Ribosomal protein S7e signature. RLvRELEKKFSgKH

Chain	Residue	Details
I	ARG78-HIS91

---

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
d	GLU60-LEU68

---

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VlKFLAAGTHLG

Chain	Residue	Details
B	VAL15-GLY26

---

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlLVVtDpraDhqpLtEasyvNLP

Chain	Residue	Details
B	PRO119-PRO143

---

site_id	PS00996
Number of Residues	9
Details	RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA

Chain	Residue	Details
W	LEU11-ALA19

---

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgCykittvFShAqtvvlCvgCStvLcqPtG

Chain	Residue	Details
c	LYS36-GLY68

---

site_id	PS01189
Number of Residues	19
Details	RIBOSOMAL_S12E Ribosomal protein S12e signature. ALQevLktAlihDGLarGI

Chain	Residue	Details
N	ALA17-ILE35

---

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVfEvSLaDL

Chain	Residue	Details
C	LEU62-LEU74

---

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RrkTGGkrkpy.HkKrKyELG

Chain	Residue	Details
J	ARG11-GLY30

---

site_id	PS01262
Number of Residues	23
Details	IF1A Eukaryotic initiation factor 1A signature. MlGnGRleamCfDGvkRlcHIrG

Chain	Residue	Details
A	MET41-GLY63

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P62267

Chain	Residue	Details
Y	LYS54
U	LYS111
e	CYS39
e	CYS42

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: 3-hydroxyproline => ECO:0000250|UniProtKB:P62266

Chain	Residue	Details
Y	PRO62
T	LYS106
h	THR96
h	THR277
E	SER224

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P62266

Chain	Residue	Details
Y	LYS135
h	TYR228
P	ASP46
P	GLY89
H	SER242
H	SER244
H	SER247

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250|UniProtKB:P62266

Chain	Residue	Details
Y	LYS37
V	LYS75
T	LYS106

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P60866

Chain	Residue	Details
V	SER93
E	ARG65
J	LYS193

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P60866

Chain	Residue	Details
V	LYS4
O	LYS43
h	SER279

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P60866

Chain	Residue	Details
h	THR316
V	LYS8
C	LYS249

---

site_id	SWS_FT_FI8
Number of Residues	10
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P62979

Chain	Residue	Details
g	LEU-26
g	LYS113
E	LYS230
g	GLY-21
g	TYR27
g	GLU29
g	ALA33
g	LYS48
g	LYS63
g	LYS107

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) => ECO:0000250|UniProtKB:P62979

Chain	Residue	Details
g	GLY76

---