6XKC

Crystal structure of E3 ligase

Summary for 6XKC

• Entry DOI: 10.2210/pdb6xkc/pdb
• Descriptor: Protein fem-1 homolog C (2 entities in total)
• Functional Keywords: ups, ubiquitin, e3 ligase, protein degradation, structural genomics, structural genomics consortium, sgc, ligase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 6
• Total formula weight: 159747.10

Authors

Yan, X.,Dong, A.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Min, J.R.,Dong, C.,Structural Genomics Consortium (SGC) (deposition date: 2020-06-26, release date: 2020-10-14, Last modification date: 2023-10-18)

• Primary citation: Yan, X.,Wang, X.,Li, Y.,Zhou, M.,Li, Y.,Song, L.,Mi, W.,Min, J.,Dong, C.; Molecular basis for ubiquitin ligase CRL2 FEM1C -mediated recognition of C-degron.; Nat.Chem.Biol., 17:263-271, 2021; PubMed: 33398170; DOI: 10.1038/s41589-020-00703-4

Experimental method

X-RAY DIFFRACTION (2.03 Å)