2KDN
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![BU of 2kdn by Molmil](/molmil-images/mine/2kdn) | Solution structure of PFE0790c, a putative bolA-like protein from the protozoan parasite Plasmodium falciparum. | Descriptor: | Putative uncharacterized protein PFE0790c | Authors: | Buchko, G.W, Yee, A, Semesi, A, Hui, R, Arrowsmith, C.H, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2009-01-12 | Release date: | 2009-01-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution-state NMR structure of the putative morphogene protein BolA (PFE0790c) from Plasmodium falciparum. Acta Crystallogr F Struct Biol Commun, 71, 2015
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2ZJC
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![BU of 2zjc by Molmil](/molmil-images/mine/2zjc) | TNFR1 selectve TNF mutant; R1-6 | Descriptor: | GLYCEROL, Tumor necrosis factor | Authors: | Mukai, Y, Yamagata, Y, Tsutsumi, Y. | Deposit date: | 2008-03-05 | Release date: | 2009-01-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-Function Relationship of Tumor Necrosis Factor (TNF) and Its Receptor Interaction Based on 3D Structural Analysis of a Fully Active TNFR1-Selective TNF Mutant J.Mol.Biol., 385, 2009
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2K21
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![BU of 2k21 by Molmil](/molmil-images/mine/2k21) | NMR structure of human KCNE1 in LMPG micelles at pH 6.0 and 40 degree C | Descriptor: | Potassium voltage-gated channel subfamily E member | Authors: | Kang, C, Tian, C, Sonnichsen, F.D, Smith, J.A, Meiler, J, George, A.L, Vanoye, C.G, Sanders, C.R, Kim, H. | Deposit date: | 2008-03-19 | Release date: | 2008-12-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel. Biochemistry, 47, 2008
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2LM4
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![BU of 2lm4 by Molmil](/molmil-images/mine/2lm4) | Solution NMR Structure of mitochondrial succinate dehydrogenase assembly factor 2 from Saccharomyces cerevisiae, Northeast Structural Genomics Consortium Target YT682A | Descriptor: | Succinate dehydrogenase assembly factor 2, mitochondrial | Authors: | Eletsky, A, Winge, D.R, Lee, H, Lee, D, Kohan, E, Hamilton, K, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J.H, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP) | Deposit date: | 2011-11-22 | Release date: | 2012-01-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of yeast succinate dehydrogenase flavinylation factor sdh5 reveals a putative sdh1 binding site. Biochemistry, 51, 2012
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7OVG
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![BU of 7ovg by Molmil](/molmil-images/mine/7ovg) | |
7OOX
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![BU of 7oox by Molmil](/molmil-images/mine/7oox) | Crystal structure of PIM1 in complex with ARC-3126 | Descriptor: | 1,2-ETHANEDIOL, Inhibitor ARC-3126, PHOSPHATE ION, ... | Authors: | Chaikuad, A, Dixon-Clarke, S.E, Nonga, O.E, Uri, A, Bullock, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2021-05-28 | Release date: | 2021-08-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family. Molecules, 26, 2021
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7OOV
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![BU of 7oov by Molmil](/molmil-images/mine/7oov) | Crystal structure of PIM1 in complex with ARC-1411 | Descriptor: | 1,2-ETHANEDIOL, Inhibitor ARC-1411, SULFATE ION, ... | Authors: | Chaikuad, A, Dixon-Clarke, S.E, Nonga, O.E, Uri, A, Bullock, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2021-05-28 | Release date: | 2021-08-04 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family. Molecules, 26, 2021
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7OOW
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![BU of 7oow by Molmil](/molmil-images/mine/7oow) | Crystal structure of PIM1 in complex with ARC-1415 | Descriptor: | 1,2-ETHANEDIOL, INHIBITOR ARC-1415, MAGNESIUM ION, ... | Authors: | Chaikuad, A, Dixon-Clarke, S.E, Nonga, O.E, Uri, A, Bullock, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2021-05-28 | Release date: | 2021-08-04 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family. Molecules, 26, 2021
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8B6T
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![BU of 8b6t by Molmil](/molmil-images/mine/8b6t) | X-ray structure of the interface optimized haloalkane dehalogenase HaloTag7 fusion to the green fluorescent protein GFP (ChemoG5-TMR) labeled with a chloroalkane tetramethylrhodamine fluorophore substrate | Descriptor: | CHLORIDE ION, Green fluorescent protein,Haloalkane dehalogenase, [9-[2-carboxy-5-[2-[2-(6-chloranylhexoxy)ethoxy]ethylcarbamoyl]phenyl]-6-(dimethylamino)xanthen-3-ylidene]-dimethyl-azanium | Authors: | Tarnawski, M, Hellweg, L, Hiblot, J. | Deposit date: | 2022-09-27 | Release date: | 2023-07-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A general method for the development of multicolor biosensors with large dynamic ranges. Nat.Chem.Biol., 19, 2023
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3URF
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![BU of 3urf by Molmil](/molmil-images/mine/3urf) | Human RANKL/OPG complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 11, soluble form, ... | Authors: | Wang, X.Q, Luan, X.D, Lu, Q.Y. | Deposit date: | 2011-11-22 | Release date: | 2012-07-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | Crystal Structure of Human RANKL Complexed with Its Decoy Receptor Osteoprotegerin J.Immunol., 189, 2012
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8B9D
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![BU of 8b9d by Molmil](/molmil-images/mine/8b9d) | Human replisome bound by Pol Alpha | Descriptor: | Cell division control protein 45 homolog, Claspin, DNA Molecule, ... | Authors: | Jones, M.L, Yeeles, J.T.P. | Deposit date: | 2022-10-05 | Release date: | 2023-08-09 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
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7P4Y
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![BU of 7p4y by Molmil](/molmil-images/mine/7p4y) | |
7P4V
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![BU of 7p4v by Molmil](/molmil-images/mine/7p4v) | |
7P50
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8G7U
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![BU of 8g7u by Molmil](/molmil-images/mine/8g7u) | |
8G7T
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![BU of 8g7t by Molmil](/molmil-images/mine/8g7t) | Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-end) | Descriptor: | Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2023-02-17 | Release date: | 2023-11-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization. Nat Commun, 14, 2023
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8G7V
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![BU of 8g7v by Molmil](/molmil-images/mine/8g7v) | Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-inter) | Descriptor: | Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2023-02-17 | Release date: | 2023-11-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization. Nat Commun, 14, 2023
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7P3I
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![BU of 7p3i by Molmil](/molmil-images/mine/7p3i) | Crystal structure of human CD40/TNFRSF5 in complex with the anti-CD40 DARPin protein | Descriptor: | Darpin, SODIUM ION, Tumor necrosis factor receptor superfamily member 5 | Authors: | Malvezzi, F, Mangold, S, Hospodarsch, T, Reichen, C, Iss, C, Lammens, A, Krapp, S, Domke, C. | Deposit date: | 2021-07-07 | Release date: | 2022-04-06 | Last modified: | 2022-05-11 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | A Multispecific Anti-CD40 DARPin Construct Induces Tumor-Selective CD40 Activation and Tumor Regression. Cancer Immunol Res, 10, 2022
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7PCH
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![BU of 7pch by Molmil](/molmil-images/mine/7pch) | Human carboxyhemoglobin bound to Staphylococcus aureus hemophore IsdB - 1:2 complex | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein B, ... | Authors: | De Bei, O, Gianquinto, E, Chirgadze, D.Y, Hardwick, S.W, Spyrakis, F, Luisi, B.F, Campanini, B. | Deposit date: | 2021-08-03 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction. Proc.Natl.Acad.Sci.USA, 119, 2022
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7PCQ
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![BU of 7pcq by Molmil](/molmil-images/mine/7pcq) | Human carboxyhemoglobin bound to Staphylococcus aureus hemophore IsdB - 1:1 complex | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein B, ... | Authors: | De Bei, O, Gianquinto, E, Chirgadze, D.Y, Hardwick, S.W, Spyrakis, F, Luisi, B.F, Campanini, B. | Deposit date: | 2021-08-03 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction. Proc.Natl.Acad.Sci.USA, 119, 2022
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7PCF
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![BU of 7pcf by Molmil](/molmil-images/mine/7pcf) | Human methemoglobin bound to Staphylococcus aureus hemophore IsdB | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein B, ... | Authors: | De Bei, O, Gianquinto, E, Chirgadze, D.Y, Hardwick, S.W, Spyrakis, F, Luisi, B.F, Campanini, B. | Deposit date: | 2021-08-03 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (5.82 Å) | Cite: | Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction. Proc.Natl.Acad.Sci.USA, 119, 2022
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7OVU
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8C30
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![BU of 8c30 by Molmil](/molmil-images/mine/8c30) | Crystal structure of 14-3-3 in complex with PyrinpS242 and a protein/peptide interface fragment | Descriptor: | 14-3-3 protein sigma, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CALCIUM ION, ... | Authors: | Lau, R, Ottmann, C. | Deposit date: | 2022-12-23 | Release date: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | 14-3-3/Pyrin complex To Be Published
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7PHG
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![BU of 7phg by Molmil](/molmil-images/mine/7phg) | MaP OF P5C3RBD Interface | Descriptor: | Heavy ChaIn variable, Light ChaIn, Surface glycoprotein | Authors: | Perez, L. | Deposit date: | 2021-08-17 | Release date: | 2021-10-13 | Last modified: | 2021-10-27 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | A highly potent antibody effective against SARS-CoV-2 variants of concern. Cell Rep, 37, 2021
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7Q03
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![BU of 7q03 by Molmil](/molmil-images/mine/7q03) | Ketol-acid reductoisomerase from Methanothermococcus thermolithotrophicus in the close state with NADP and Mg2+ | Descriptor: | 1,2-ETHANEDIOL, 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, GLYCEROL, ... | Authors: | Lemaire, O.N, Mueller, M, Wagner, T. | Deposit date: | 2021-10-14 | Release date: | 2021-12-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Rearrangements of a Dodecameric Ketol-Acid Reductoisomerase Isolated from a Marine Thermophilic Methanogen. Biomolecules, 11, 2021
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