7OVG

The C146A variant of an amidase from Pyrococcus horikoshii with bound acetamide

Summary for 7OVG

Entry DOI	10.2210/pdb7ovg/pdb
Descriptor	CN hydrolase domain-containing protein, ACETAMIDE, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	amidase, nitrilase superfamily, hydrolase
Biological source	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Total number of polymer chains	2
Total formula weight	60090.02
Authors	Su, S.,Makumire, S.,Sewell, B.T. (deposition date: 2021-06-14, release date: 2021-07-21, Last modification date: 2024-01-31)
Primary citation	Makumire, S.,Su, S.,Weber, B.W.,Woodward, J.D.,Wangari Kimani, S.,Hunter, R.,Sewell, B.T. The structures of the C146A variant of the amidase from Pyrococcus horikoshii bound to glutaramide and acetamide suggest the basis of amide recognition. J.Struct.Biol., 214:107859-107859, 2022 Cited by PubMed: 35439644 DOI: 10.1016/j.jsb.2022.107859 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation